Clinical Development RisksRisks include clinical development risk, competitor risk, novel modality risk, commercialization risk, reimbursement risk, pricing risk, business development risk, capital market and dilution risk, and disruptions to clinical trials owing to the war in Eastern Europe.
Financial PerformanceARWR remains engaged with FDA and potential strategic financing partners to resolve balance sheet overhang, which also drove 11/30 sell-off (-25%) and PT lowering from $60 to $50.
Program ViabilityEnded development of preclinical program ARO-SOD1 and partnered HZN-457 due to a lack of commercial viability.