Plozasiran Clinical Advancements
Plozasiran has shown promising results in various trials, including the Phase III PALISADE study, and has potential for multiple indications such as FCS, SHTG, and mixed hyperlipidemia. The drug achieved up to 80% reduction in triglycerides in the PALISADE study.
Strategic Financing
Arrowhead secured a $500 million senior secured credit facility from Sixth Street, enhancing liquidity for global commercial launches and clinical trials.
Ongoing Pipeline Expansion
Arrowhead's pipeline includes multiple promising candidates, such as ARO-RAGE for asthma and ARO-INHBE for obesity, with plans to file CTAs for new candidates by the end of the year.
Positive Commercial Preparation
Arrowhead is building a robust commercial infrastructure for the launch of plozasiran, with a focus on patient support and market readiness.
Milestone Payment
Arrowhead received a $50 million milestone payment from Royalty Pharma, strengthening its financial position.