Clinical Trial SetbacksIncyte has paused enrollment for its Phase 2 trial in chronic spontaneous urticaria due to preclinical toxicology findings, casting doubt on the pipeline's reliability.
Pipeline ChallengesDevelopment of zilurgisertib, the ALK2 inhibitor, has been discontinued, adding to a growing list of pipeline misses.
Revenue ChallengesOpzelura revenue will be challenged by lower tube usage, raising concerns over future financial performance.