Potential Market OpportunityPovo could be positioned largely in post-biologic in the US, which could represent a potentially meaningful opportunity.
Safety ProfilePovorcitinib had a favorable safety profile with acne being the most common TEAE and no MACE or embolic/thromboembolic adverse events reported.
Treatment EfficacyPovorcitinib demonstrated a statistically significant difference in HiSCR50 against placebo in both trials, indicating its efficacy in treating moderate/severe hidradenitis suppurativa.