Market CompetitionNew diagnoses are slowing down, so the future market will be more about competition rather than expanding the pie.
Product Development And Pipeline IssuesDevelopment of ALN-KHK, an RNAi therapeutic targeting ketohexokinase for type 2 diabetes, has been suspended.
Regulatory And Reimbursement ChallengesAmvuttra is either not covered or 'effectively' not covered in several Medicare segments, disadvantaged in MAPD & non-Medicare, and advantaged in Medigap-related segments.