Financial PerformanceUnaudited full-year revenue for 2024 was $814 million, above consensus of $784 million.
Regulatory ProgressPTC continues to execute well, with Upstaza's PDUFA and sepiapterin's set for approval, and there is anticipation for both approvals.
Strategic PartnershipsPTC signed an exclusive global license agreement with NVS for PTC518 in Huntington's disease in exchange for $1B upfront, up to $1.9B in development, regulatory and sales milestones, a 40/60 profit share in the U.S., and double-digit tiered royalties ex-U.S.