PTC Therapeutics (PTCT) AI Stock Analysis

• Market Cap: $3.85B
• Dividend Yield: N/A
• Average Volume (3M): 1.04M
• Price to Earnings (P/E): 7.6
• Beta (1Y): 1.48
• Revenue Growth: 91.12%
• EPS Growth: N/A
• Country: US
• Employees: 939
• Sector: Healthcare
• Sector Strength: 37
• Industry: Biotechnology
• EPS (TTM): 10.04
• Shares Outstanding: 79,257,020
• 10 Day Avg. Volume: 851,485
• 30 Day Avg. Volume: 1,036,832
• PEG Ratio: 0.02
• Price to Book (P/B): -20.80
• Price to Sales (P/S): 0.00
• P/FCF Ratio: 5.27
• Enterprise Value/Market Cap: 0.74
• Enterprise Value/Revenue: 0.65
• Enterprise Value/Gross Profit: 1.65
• Enterprise Value/Ebitda: 6.04
• 1Y Price Target: $62.08
• Price Target Upside: 25.52% Upside
• Rating Consensus: Moderate Buy
• Number of Analyst Covering: 14

• Rating: 69 Neutral
• Price Target: $53.00 ▲(7.16%Upside)

PTC Therapeutics has made notable financial improvements with strong revenue growth and positive cash flow, leading to a good financial performance score. The valuation is attractive due to a low P/E ratio. However, the technical analysis suggests neutral momentum, and potential financial instability from negative equity remains a concern.

Positive Factors

Financial Performance

PTC Therapeutics has a strong balance sheet with approximately $20 per share in net cash, which resonates well with investors.

Market Reach

Review of approval applications is ongoing in several countries including Japan and Brazil, which could expand market reach.

Sales Potential

Meaningful upside to consensus based on survey results suggests higher sales potential for Sephience.

Negative Factors

Risks and Challenges

Safety, clinical, regulatory, competition and financing are all risks inherent in commercial stage biotech including PTCT.

PTC Therapeutics Business Overview & Revenue Model

Company Description

PTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to patients with rare disorders. Its portfolio pipeline includes commercial products and product candidates in various stages of development, including clinical, pre-clinical and research and discovery stages, focuses on the development of treatments for multiple therapeutic areas, such as rare diseases. The company offers Translarna and Emflaza for the treatment of Duchenne muscular dystrophy in the European Economic Area and the United States, as well as to treat nonsense mutation Duchenne muscular dystrophy in Brazil and Russia; commercializes Tegsedi and Waylivra for the treatment of rare diseases in Latin America and the Caribbean; and markets Evrysdi for the treatment of spinal muscular atrophy in adults and children two months and older in Brazil. The company's splicing platform includes PTC518, which is being developed for the treatment of Huntington's disease. PTC Therapeutics, Inc. has collaborations with F. Hoffman-La Roche Ltd and Hoffman-La Roche Inc., as well as the Spinal Muscular Atrophy Foundation to advance drug discovery and development research in regenerative medicine; and Akcea Therapeutics, Inc. to commercialize Tegsedi and Waylivra for the treatment of rare diseases in Latin America and the Caribbean. PTC Therapeutics, Inc. was incorporated in 1998 and is headquartered in South Plainfield, New Jersey.

How the Company Makes Money

PTC Therapeutics primarily generates revenue through the sale of its pharmaceutical products that are developed to treat rare and orphan diseases. The company's revenue model is based on the commercialization of its FDA-approved drugs, which are sold both directly to healthcare providers and through distribution partnerships. Key revenue streams include sales of its flagship products such as Translarna (ataluren) for the treatment of nonsense mutation Duchenne muscular dystrophy and Emflaza (deflazacort), a corticosteroid for Duchenne muscular dystrophy. Additionally, PTC Therapeutics engages in strategic collaborations and licensing agreements with other biotechnology and pharmaceutical companies, which provide additional revenue through milestone payments and royalties. The company's focus on niche markets with high unmet medical needs often allows for premium pricing of its treatments, contributing significantly to its earnings.

PTC Therapeutics Financial Statement Overview

Summary

PTC Therapeutics has shown a significant financial turnaround with strong revenue growth and improved profitability. The company has managed its cash flows effectively, leading to positive free cash flow. However, the negative equity position and high liabilities indicate potential financial instability.

Income Statement

PTC Therapeutics has shown a remarkable turnaround in its financial performance. The TTM (Trailing-Twelve-Months) gross profit margin is strong at 96.52%, indicating efficient cost management. The net profit margin has improved significantly to 33.55% in the TTM, reflecting a positive shift from previous losses. Revenue growth has been robust, with a 119.73% increase from 2024 to the TTM period. The EBIT and EBITDA margins have also turned positive, demonstrating improved operational efficiency. However, the company has experienced volatility in past years, which could pose a risk if not managed carefully.

Balance Sheet

The balance sheet of PTC Therapeutics presents a mixed picture. The debt-to-equity ratio is not meaningful due to negative stockholders' equity, indicating potential financial instability. However, the company has a strong cash position, with cash and equivalents exceeding total debt, resulting in negative net debt. The equity ratio is negative, which is a concern, but the company has managed to improve its asset base over time. The negative equity and high liabilities suggest a need for careful financial management to ensure long-term sustainability.

Cash Flow

PTC Therapeutics has shown a significant improvement in cash flow metrics. The TTM free cash flow is positive at $744.24 million, a substantial increase from previous negative figures, indicating better cash generation. The operating cash flow to net income ratio is 1.16, suggesting that the company is generating cash efficiently relative to its net income. The free cash flow to net income ratio is 1.25, further highlighting strong cash flow management. Despite these improvements, the company must continue to focus on maintaining positive cash flows to support its operations and growth.

Breakdown	TTM	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020
Income Statement
Total Revenue	1.77B	806.78M	937.82M	698.80M	538.59M	380.77M
Gross Profit	1.71B	749.38M	872.34M	654.12M	506.26M	361.82M
EBITDA	833.62M	-120.46M	-330.34M	-367.78M	-374.44M	-297.00M
Net Income	594.84M	-363.30M	-626.60M	-559.02M	-523.90M	-438.16M
Balance Sheet
Total Assets	2.66B	1.71B	1.90B	1.71B	1.94B	2.21B
Cash, Cash Equivalents and Short-Term Investments	2.03B	1.14B	876.74M	410.70M	773.38M	1.10B
Total Debt	389.62M	389.30M	2.23B	703.63M	431.43M	420.44M
Total Liabilities	2.84B	2.80B	2.71B	2.05B	1.94B	1.73B
Stockholders Equity	-185.76M	-1.10B	-818.55M	-347.09M	1.44M	481.98M
Cash Flow
Free Cash Flow	744.24M	-114.19M	-279.04M	-509.11M	-336.66M	-250.05M
Operating Cash Flow	691.65M	-107.69M	-158.42M	-356.65M	-251.33M	-194.07M
Investing Cash Flow	-25.25M	44.18M	-176.74M	290.18M	219.18M	-561.55M
Financing Cash Flow	264.74M	255.87M	646.40M	167.95M	20.88M	668.72M

PTC Therapeutics Technical Analysis

• Technical Analysis Sentiment: Positive
• Last Price: 49.46
• 50DMA: Positive
• 100DMA: Positive
• 200DMA: Positive
• MACD: Positive
• RSI: Neutral
• STOCH: Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PTCT, the sentiment is Positive. The current price of 49.46 is below the 20-day moving average (MA) of 49.48, above the 50-day MA of 48.16, and above the 200-day MA of 46.50, indicating a neutral trend. The MACD of -0.09 indicates Positive momentum. The RSI at 51.78 is Neutral, neither overbought nor oversold. The STOCH value of 57.75 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PTCT.

PTC Therapeutics Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
PTCT	69 Neutral	$3.85B	7.60	33.08%	―	91.12%	―
RYTM	62 Neutral	$5.69B	―	-418.97%	―	48.88%	39.30%
ACLX	58 Neutral	$3.80B	―	-35.56%	―	-41.66%	-180.15%
Sector *	55 Neutral	€4.64B	17.01	-50.16%	3.66%	15.32%	-9.52%
RNA	53 Neutral	$3.79B	―	-34.19%	―	-17.87%	-1.89%
RARE	50 Neutral	$2.79B	―	-386.33%	―	33.46%	26.72%

PTC Therapeutics Corporate Events

PTC Therapeutics Elects Directors at Annual Meeting

PTC Therapeutics held its Annual Meeting on June 17, 2025, where stockholders elected three Class III directors to serve until the 2028 annual meeting. Additionally, the appointment of Ernst & Young LLP as the independent registered public accounting firm for the fiscal year ending December 31, 2025, was ratified. The stockholders also approved a non-binding advisory proposal on named executive officer compensation.

The most recent analyst rating on (PTCT) stock is a Buy with a $63.00 price target. To see the full list of analyst forecasts on PTC Therapeutics stock, see the PTCT Stock Forecast page.

PTC Therapeutics Reports Strong Q1 2025 Financial Results

PTC Therapeutics reported strong financial results for the first quarter of 2025, with a total net product and royalty revenue of $190 million. The company highlighted a positive CHMP opinion for Sephience, which is expected to enhance its global market launch. PTC’s cash position of over $2 billion supports its commercial and R&D activities, aiming for cashflow breakeven without additional capital. The company also updated its full-year 2025 financial guidance, anticipating revenue between $650 million and $800 million, driven by existing and potential new product launches.

PTC Therapeutics Reports Positive Phase 2 Study Results

PTC Therapeutics announced positive results from its Phase 2 PIVOT-HD study of PTC518 for Huntington’s disease, achieving the primary endpoint of reducing blood Huntingtin protein levels. The study showed favorable safety and tolerability, with dose-dependent clinical benefits observed over 12 and 24 months, potentially positioning PTC518 as a disease-modifying therapy for Huntington’s disease.