Efficacy ConcernsAnalysts are less confident in overall survival benefit, which KOLs are looking for, given DFS benefit expected to be small.
Study DelayNTRA announced that the highly anticipated ALTAIR CRC study is getting pushed out by 4 months, which might raise questions if it will impact timelines from the guidelines committee at NCCN.
Trial Design IssuesConcerns exist around the trial design of ALTAIR, including LONSURF being introduced as 2nd or 3rd line therapy.