Commercial UncertaintyRegarding the commercial opportunity, management notes that this will be hard to answer until the profile is known, adding that if data replicates previous results, questions will answer themselves.
Competitive PressureThe lead asset varegacestat is a Phase 3 oral small molecule gamma-secretase inhibitor with one marketed competitor for rare progressing desmoid tumors, heading into a pivotal topline readout.
Financial SustainabilityAs of December 31st 2024, IMNM has $217.3M in cash and investments, excluding likely net proceeds of $161.6M from financing, providing an operating runway into March 2025.