Market CompetitionBetween the growing prophylaxis market and the increased competition in the on-demand therapy space, it will be an uphill battle to capture meaningful market share.
Strategic ReviewFollowing a strategic review of the Factor XIIa program, the company determined that the most promising indications for development lie outside the company's core capabilities.
Treatment DemandAs the prophylactic treatment landscape continues to expand and improve, patients' disease burden will lessen resulting in a reduced need for on-demand HAE therapy.