Clinical DevelopmentThe first patient was dosed in a Ph1 trial of FHD-909 in SMARCA4-mutated cancers, with NSCLC as the target patient population.
Market PotentialFHD-909 targets a substantial market of about 5% of all solid tumors and up to 10% of NSCLC, with NSCLC as the primary focus.
Pipeline StrategyThe decision to discontinue efforts with FHD-286 strengthens the company's focus on FHD-909, along with earlier-stage pipeline programs including Foghorn's CBP, EP300, and ARID1B degraders.