Clinical Study ChallengesThe company stated that most of the patients with ‘hot’ tumors in the dose expansion study that have been enrolled so far have progressed despite prior anti-PD-1 therapy or are PD-L1 negative, which would be unlikely to respond to re-challenge with anti-PD-1 therapy alone.
Data Update DelaysThe anticipated data update for the SNS-101 study has been delayed to 1H25, as the company seeks more duration data.
Regulatory RisksRisks associated with the stock include commercial, regulatory, clinical, manufacturing, financial, liability, and intellectual property concerns.