Clinical ResultsFarabursen demonstrated continued target engagement via reductions in polycystin-1/PC1 and polycystin-2/PC2, showing mechanistic dose response.
Financial PositionThe company ended with $87.3M in cash, cash equivalents, and investments, expected to provide runway into 1H26.
Regulatory ProgressRegulus disclosed positive interim data from Cohort 4 with farabursen (RGLS8429) in ADPKD and provided a regulatory update, reaching alignment on key components of a single pivotal study for Accelerated Approval.