Market CompetitionThe Eylea franchise has already been facing stiff competition from Roche's Vabysmo, but a new upset came with recent news that Amgen will be launching a biosimilar version of Eylea SD soon, calling into question the trajectory of the franchise.
Product Launch ChallengesThe EYLEA HD launch and switch from 2mg EYLEA has been more challenging than expected, with meaningful acceleration not anticipated until much later, complicating the outlook for EYLEA.
Sales PerformanceEylea HD sales fell short of expectations, which could be a concern for investors as REGN faces a tougher challenge after the recent launch of the first biosimilar.