Want to see ORKA full AI Analyst Report?
ORKA Stock Chart & Stats
$92.16
-$1.96(-2.13%)
At close: 4:00 PM EDT
$92.16
-$1.96(-2.13%)
Day’s Range― - ―
52-Week Range$12.84 - $97.78
Previous Close$89.8
Volume744.14K
Average Volume (3M)1.51M
Market Cap
$5.56B
Enterprise Value$2.61B
Total Cash (Recent Filing)$388.83M
Total Debt (Recent Filing)$1.81M
Price to Earnings (P/E)―
Beta1.08
Next Earnings
Aug 17, 2026EPS Estimate
-0.51Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-2.39
Shares Outstanding60,312,100
10 Day Avg. Volume970,993
30 Day Avg. Volume1,505,454
Financial Highlights & Ratios
PEG Ratio0.24
Price to Book (P/B)2.93
Price to Sales (P/S)0.00
P/FCF Ratio-15.64
Enterprise Value/Market Cap0.47
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-36.72K
Enterprise Value/Ebitda-22.44
Forecast
1Y Price Target
$147.63Price Target Upside60.18% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering10
EPS Forecast (FY)-2.11
Revenue Forecast (FY)N/A
Bulls Say, Bears Say
Bulls Say
Low Leverage And Large Equity BaseExtremely low debt and a large equity base materially reduce refinancing and interest-rate risk for a pre-revenue biotech. This structural financial flexibility supports multi-year clinical programs, strategic partnering, and optionality without immediate reliance on dilutive financing.
Differentiated Phase 2a Efficacy And TolerabilityHigh skin‑clearance rates and a placebo‑comparable safety profile provide durable clinical differentiation versus IL‑23 class peers. Long-acting pharmacokinetics that enable annual dosing could create a sustainable competitive advantage through convenience, adherence, and commercial premium.
Completed Equity Offering Strengthens Cash RunwayA sizable post-offering cash position materially extends runway to fund ongoing Phase 2b enrollment and additional trials. This reduces near-term financing pressure, enabling disciplined development decisions and more favorable timing on partnering or commercial planning.
Bears Say
Pre-revenue With Widening Net LossesBeing pre-revenue with growing operating losses means long lead times to commercialization and profitability. Persistent negative returns on equity and expanding deficits increase dependency on external capital and raise execution risk across clinical and commercial milestones.
Heavy And Rising Cash BurnOperating and free cash outflows have increased materially year-over-year, signaling sustained funding needs. Even with current liquidity, the structural burn rate pressures long-term funding strategy and could force dilutive raises or constrain R&D depth if trial timelines lengthen.
IL-23 License Dosing Restrictions Limit Strategic ScopeContractual dosing limits constrain development and partnering options in inflammatory bowel disease for years, narrowing near-term indication expansion. These structural restrictions can delay market entry, reduce addressable market access, and complicate strategic collaborations or transactions.
ORKA FAQ
What was Oruka Therapeutics, Inc.’s price range in the past 12 months?
Oruka Therapeutics, Inc. lowest stock price was $12.84 and its highest was $97.78 in the past 12 months.
What is Oruka Therapeutics, Inc.’s market cap?
Oruka Therapeutics, Inc.’s market cap is $5.56B.
When is Oruka Therapeutics, Inc.’s upcoming earnings report date?
Oruka Therapeutics, Inc.’s upcoming earnings report date is Aug 17, 2026 which is in 20 days.
How were Oruka Therapeutics, Inc.’s earnings last quarter?
Oruka Therapeutics, Inc. released its earnings results on May 13, 2026. The company reported -$0.48 earnings per share for the quarter, beating the consensus estimate of -$0.547 by $0.067.
Is Oruka Therapeutics, Inc. overvalued?
According to Wall Street analysts Oruka Therapeutics, Inc.’s price is currently Undervalued.
Does Oruka Therapeutics, Inc. pay dividends?
Oruka Therapeutics, Inc. pays a Notavailable dividend of $19.356 which represents an annual dividend yield of N/A. See more information on Oruka Therapeutics, Inc. dividends here
What is Oruka Therapeutics, Inc.’s EPS estimate?
Oruka Therapeutics, Inc.’s EPS estimate is -0.51.
How many shares outstanding does Oruka Therapeutics, Inc. have?
Oruka Therapeutics, Inc. has 60,312,100 shares outstanding.
What happened to Oruka Therapeutics, Inc.’s price movement after its last earnings report?
Oruka Therapeutics, Inc. reported an EPS of -$0.48 in its last earnings report, beating expectations of -$0.547. Following the earnings report the stock price went up 1.14%.
Which hedge fund is a major shareholder of Oruka Therapeutics, Inc.?
Currently, no hedge funds are holding shares in ORKA
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Oruka Therapeutics Stock Smart Score
Neutral
1
2
3
4
5
6
7
8
9
10
Analyst Consensus
Strong Buy
Average Price Target:
$147.63 (60.18% Upside)
$147.63 (60.18% Upside)
Blogger Sentiment
Bullish
ORKA Sentiment 70%
Sector Average ―
Sector Average ―
Hedge Fund Trend
Decreased
By 1.2M Shares
Last Quarter.
Last Quarter.
Insider Transactions
Sold Shares
Worth $300.2M over
the Last 3 Months
the Last 3 Months
Crowd Wisdom
Positive
Last 7 Days ▼ 0.2%
Last 30 Days ▲ 3.2%
Last 30 Days ▲ 3.2%
Technicals
SMA
Positive
20 days / 200 days
Momentum
547.64%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
33.77%
Trailing 12-Months
Company Description
Oruka Therapeutics, Inc.
Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions. The company also develops ORKA-003 for targeting an undisclosed pathway; and ORKA-021, a sequential combination regimen of ORKA-002 and ORKA-001. Oruka Therapeutics, Inc. is headquartered in Menlo Park, California.
ORKA Stock 12 Month Forecast
Average Price Target
$147.63
▲(60.18% Upside)
Technical Analysis
Verastem
―
AnaptysBio
―
Compass Therapeutics
―
Olema Pharmaceuticals
―
Bicara Therapeutics Inc.
―
Ownership Overview
8.27% Insiders
16.72% Mutual Funds
1.01% Other Institutional Investors
59.96% Public Companies and
Individual Investors











