Adverse Reactions46.4% of patients treated with the combination experienced a G3+ TRAE, with G3 ALT/AST elevations occurring in 14% and 7% of patients, respectively; 7.1% of patients discontinued treatment due to a TRAE.
Study EnrollmentEnrollment in the Ph1/1b study is currently on hold due to possible changes in the standard of care in an earlier line of therapy.
Trial LimitationsThe current research in squamous cancer of the anal canal is not included in the primary model, with focus remaining on other data updates.