Market ValuationSome 1L ALK value is already priced into NUVL shares, raising questions about whether the predominantly 3L+ data at ESMO can drive upside to NUVL shares.
Price Target RisksKey risks to the 12-month price target include clinical, regulatory, and commercial risks, potential emergence of new competitors, and dilutive financing beyond what has been anticipated.
Regulatory ApprovalThere is more debate around the potential for a single arm path to 2L ALK approval without needing a randomized trial.