Market CompetitionThe announcement that Lasix ONYU will be priced at a wholesale acquisition cost of ~50% of that of Furoscix was the largest driver of MNKD weakness.
Side EffectsThe most frequently documented side effect from real world use of Afrezza is lack of efficacy, and data revealed that under-dosing was the reason.
Statistical SignificanceTwo secondary endpoints, time to first acute exacerbation and overall survival at week 52, did not reach statistical significance, likely due to the small number of events in both cohorts.