Clinical ProfileBarzolvolimab represents a best-in-class mast cell targeting agent with stellar efficacy and a consistent, acceptable safety profile across two large Phase 2 urticaria studies.
Efficacy In Eosinophilic EsophagitisClinical and commercial opportunity for barzolvolimab in eosinophilic esophagitis, aiming for efficacy on par or better than existing treatments with less-frequent dosing.
Market OpportunityCelldex's unique mast cell-depleting mechanism & attributes offer a differentiated, first-in-class/best-in-class profile that stands to unlock significant commercial opportunity in urticaria and other mast cell-driven diseases.