SER-155 Progress and Breakthrough Therapy Designation
Seres advanced their lead program SER-155, aimed at preventing life-threatening bloodstream infections, with a 77% relative risk reduction observed in clinical trials. The FDA granted breakthrough therapy designation for SER-155.
Positive Biomarker and Clinical Data
Exploratory biomarker results support the efficacy of SER-155, indicating a significant reduction in bloodstream infections and positive impacts on systemic immune and inflammatory responses.
Financial Improvements
Net loss from continuing operations decreased from $190.1 million in 2023 to $125.8 million in 2024. The company is now debt-free and expects to fund operations into Q1 2026.
Robust Market Opportunity for SER-155
Market research with healthcare professionals and payers indicates strong interest in SER-155 for preventing bloodstream infections, with significant commercial potential in the allo-HSCT market.