Phase One Study of KT61 Initiated
Chimera Therapeutics has started the phase one study of KT61, a first-in-class oral STAT6 degrader. This marks the first STAT6 medicine to enter clinical development, with potential to transform treatment paradigms for diseases like atopic dermatitis, asthma, and COPD.
KT474 Program Advances to Phase Two B
The KT474, an IRAK4 degrader, is transitioning to fully powered phase two B studies with partner Sanofi, aiming for a faster path to phase three registration.
Introduction of KT295 as Lead Candidate
KT295, a new TIC2 clinical candidate, has shown greater in vivo activity compared to KT294, with potential to match human TIC2 loss-of-function mutations.
Strong Financial Position
Chimera Therapeutics raised approximately $600 million in 2024, providing a cash runway into mid-2027, supporting their expanding pipeline.