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Karyopharm Therapeutics (KPTI)
NASDAQ:KPTI
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KPTI Stock Chart & Stats
Day’s Range$0 - $0
52-Week Range$0.62 - $1.95
Previous Close$0.79
Volume667.18K
Average Volume (3M)755.49K
Market Cap
$102.01M
Enterprise Value$66.26M
Total Cash (Recent Filing)$133.53M
Total Debt (Recent Filing)$97.78M
Price to Earnings (P/E)―
Beta1.50
Next Earnings
Feb 27, 2025EPS Estimate
-$0.25Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-1.14
Shares Outstanding125,314,506
10 Day Avg. Volume767,036
30 Day Avg. Volume755,488
Standard Deviation0.20
R-Squared0.00156
Alpha-0.02
Financial Highlights & Ratios
Price to Book (P/B)-0.63
Price to Sales (P/S)0.69
Price to Cash Flow (P/CF)-1.30
P/FCF Ratio0.00
Enterprise Value/Market CapN/A
Enterprise Value/Revenue0.45
Enterprise Value/Gross Profit0.47
Enterprise Value/Ebitda-1.09
Forecast
1Y Price Target
$4.50Price Target Upside482.15% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering6
Karyopharm Therapeutics News
PremiumCompany Announcements
Karyopharm Therapeutics Appoints New Chief Accounting Officer
PremiumCompany Announcements
Karyopharm Therapeutics Inc. Reports Q3 2024 EarningsPremiumCompany Announcements
Karyopharm Therapeutics Updates Phase 3 SENTRY TrialBulls Say, Bears Say
Bulls Say
Clinical TrialsKaryopharm Therapeutics has made encouraging changes in the trial design for the Phase 3 SENTRY study in myelofibrosis, which are supported by the FDA.
Market PotentialThe management estimates around $1 billion in peak revenue for myelofibrosis in the US, indicating significant market potential.
Regulatory ApprovalsKaryopharm announced reimbursement decisions in France and Italy, and approvals for Xpovio in Turkey, South Korea, Thailand, and Malaysia.
Bears Say
Clinical TrialsEnrollment for its pivotal XPORT-MM-031 Phase III study evaluating selinexor in combination with pomalidomide and dexamethasone had slowed down due to increasing competition from other clinical trials in multiple myeloma.
Regulatory ChallengesThe company has made changes to the trial design for the pivotal Phase 3 trial evaluating Xpovio combined with Pomalyst and dexamethasone, pending regulatory feedback.
Sales PerformanceXpovio sales were up quarter-over-quarter but down year-over-year, indicating some challenges in maintaining consistent growth.
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Ownership Overview
2.34% Insiders
9.64% Mutual Funds
20.26% Other Institutional Investors
60.03% Public Companies and
Individual Investors
Risk Analysis
Main Risk Category
Tech & InnovationRisks related to the company’s reliance on technology and ability to make innovative products
Website Traffic
Sorry, No Data AvailableThere is no website visitor data available for this stock.
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KPTI FAQ
What was Karyopharm Therapeutics’s price range in the past 12 months?
Karyopharm Therapeutics lowest stock price was $0.62 and its highest was $1.95 in the past 12 months.
What is Karyopharm Therapeutics’s market cap?
Currently, no data Available
When is Karyopharm Therapeutics’s upcoming earnings report date?
Karyopharm Therapeutics’s upcoming earnings report date is Feb 27, 2025 which is in 98 days.
How were Karyopharm Therapeutics’s earnings last quarter?
Karyopharm Therapeutics released its earnings results on Nov 05, 2024. The company reported -$0.26 earnings per share for the quarter, beating the consensus estimate of -$0.263 by $0.003.
Is Karyopharm Therapeutics overvalued?
According to Wall Street analysts Karyopharm Therapeutics’s price is currently Undervalued.
Does Karyopharm Therapeutics pay dividends?
Karyopharm Therapeutics does not currently pay dividends.
What is Karyopharm Therapeutics’s EPS estimate?
Karyopharm Therapeutics’s EPS estimate is -$0.25.
How many shares outstanding does Karyopharm Therapeutics have?
Karyopharm Therapeutics has 125,314,510 shares outstanding.
What happened to Karyopharm Therapeutics’s price movement after its last earnings report?
Karyopharm Therapeutics reported an EPS of -$0.26 in its last earnings report, beating expectations of -$0.263. Following the earnings report the stock price went down -9.677%.
Which hedge fund is a major shareholder of Karyopharm Therapeutics?
Among the largest hedge funds holding Karyopharm Therapeutics’s share is Woodline Partners LP. It holds Karyopharm Therapeutics’s shares valued at 111K.
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Karyopharm Therapeutics Stock Smart Score
Unlock Smart Score
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Analyst Consensus
Strong Buy
Average Price Target:
$4.50 (482.15% Upside)
$4.50 (482.15% Upside)
Blogger Sentiment
Bullish
KPTI Sentiment 100%
Sector Average 72%
Sector Average 72%
Crowd Wisdom
Positive
Last 7 Days ▼ 1.8%
Last 30 Days ▲ 3.0%
Last 30 Days ▲ 3.0%
Technicals
SMA
Negative
20 days / 200 days
Momentum
1.79%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
-29.81%
Trailing 12-Months
Company Description
Karyopharm Therapeutics
Karyopharm Therapeutics, Inc. is an oncology-focused pharmaceutical company dedicated to the discovery, development, and commercialization of novel first-in-class drugs directed against nuclear export and related targets for the treatment of cancer and other major diseases. Its SINE compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm's lead compound, XPOVIOTM (selinexor), received accelerated approval from the FDA in combination with dexamethasone as a treatment for patients with heavily pretreated multiple myeloma. A Marketing Authorization Application for selinexor is also currently under review by the European Medicines Agency (EMA). In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development. The company was founded by Joseph Araujo, Ronald A. DePinho, Pamela A Silver, Giulio Draetta, Michael G. Kauffman and Sharon Shacham on December 22, 2008 and is headquartered in Newton, MA.
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KPTI Company Deck
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KPTI Earnings Call
Q3 2024
0:00 / 0:00
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KPTI Stock 12 Month Forecast
Average Price Target
$4.50
▲(482.15% Upside)
Technical Analysis
Best Analysts Covering KPTI
1 Year
1 Year Success Rate
5/27 ratings generated profit
1 Year Average Return
-40.25%
reiterated a buy rating 16 days ago
Copying Edward White's trades and holding each position for 1 Year would result in 18.52% of your transactions generating a profit, with an average return of -40.25% per trade.
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