Endpoint NoveltyOn the regulatory front, the EMACC endpoint correlates with the gold standard CDR-SB endpoint, which should help the FDA crosswalk the readout of the relatively novel primary EMACC endpoint.
Financial ConcernsINmune announced a $13M equity financing, which should extend the runway through the P2 data.
Trial ComplexityThe INmune blinded interim data is showing stat-sig correlation between EMACC and CDR, EMACC reliability, and EMACC differentiation in patients with different CDR ratings.