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Guardant Health (GH)
NASDAQ:GH

Guardant Health (GH) AI Stock Analysis

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GHGuardant Health
(NASDAQ:GH)
53Neutral
Guardant Health shows strong revenue growth and promising product developments, as highlighted in the earnings call, which supports a positive outlook. However, significant financial challenges and mixed technical indicators temper the overall score. Valuation concerns due to lack of profitability further impact the score, resulting in a moderate overall assessment.
Positive Factors
Product Development
Product launch catalysts such as G360 Tissue and Shield v2, along with data readouts, could drive the stock higher.
Revenue Growth
Clinical testing revenue grew 35% supported by clinical test volume growth of 24%.
Negative Factors
Balance Sheet
Debt exchange mitigates balance sheet overhang.

Guardant Health (GH) vs. S&P 500 (SPY)

Guardant Health Business Overview & Revenue Model

Company DescriptionGuardant Health, Inc. is a precision oncology company, which engages in provision of precision oncology testing and development services. It focuses performing blood tests, vast data sets, and advanced analytics to conquer cancer. The company was founded by Helmy Eltoukhy and AmirAli H. Talasaz in 2012 and is headquartered in Redwood City, CA.
How the Company Makes MoneyGuardant Health generates revenue through the sale of its proprietary liquid biopsy tests, which are used by healthcare providers for cancer diagnosis, treatment selection, and ongoing patient monitoring. The company's revenue model is primarily based on the volume of tests conducted and reimbursed by healthcare payers, including insurance companies and government programs. Additionally, Guardant Health collaborates with pharmaceutical companies to support clinical trials and drug development, providing another stream of revenue. Strategic partnerships and licensing agreements further enhance its earnings potential by expanding its market reach and technological capabilities.

Guardant Health Financial Statement Overview

Summary
Guardant Health's financial performance is challenged by negative EBIT and net income margins, high debt levels, and negative free cash flows. Despite strong revenue growth, these factors indicate significant profitability and leverage issues.
Income Statement
42
Neutral
Guardant Health has shown consistent revenue growth over the years, indicating strong market demand. However, the company continues to operate at a loss with negative EBIT and net income margins, suggesting challenges with profitability and cost management.
Balance Sheet
30
Negative
The balance sheet reveals a high debt-to-equity ratio due to negative stockholders' equity, indicating financial instability and potential liquidity risks. The negative equity ratio further highlights a leverage concern, which could restrict future financing options.
Cash Flow
35
Negative
Cash flow statements show a negative free cash flow, reflecting operational challenges in generating cash. The company has a history of negative operating cash flows, which are concerning for long-term sustainability without external financing.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
739.02M563.95M449.54M373.65M286.73M
Gross Profit
449.22M336.90M293.21M250.74M194.19M
EBIT
-443.59M-564.73M-544.38M-411.00M-254.95M
EBITDA
-390.12M-433.31M-614.91M-359.62M-225.07M
Net Income Common Stockholders
-436.37M-479.45M-654.59M-384.77M-246.28M
Balance SheetCash, Cash Equivalents and Short-Term Investments
839.98M1.17B1.01B932.75M1.79B
Total Assets
1.49B1.79B1.61B2.20B2.27B
Total Debt
1.34B1.35B1.37B1.36B847.86M
Net Debt
810.51M220.23M1.23B868.67M14.88M
Total Liabilities
1.63B1.63B1.55B1.56B916.19M
Stockholders Equity
-139.65M158.68M60.18M645.00M1.30B
Cash FlowFree Cash Flow
-274.94M-345.46M-386.92M-284.05M-157.99M
Operating Cash Flow
-239.86M-324.98M-309.46M-209.02M-103.93M
Investing Cash Flow
-261.31M840.25M149.82M-63.16M-617.09M
Financing Cash Flow
-996.00K477.38M-189.09M-66.82M1.41B

Guardant Health Technical Analysis

Technical Analysis Sentiment
Positive
Last Price42.66
Price Trends
50DMA
41.17
Positive
100DMA
34.80
Positive
200DMA
31.32
Positive
Market Momentum
MACD
-0.29
Positive
RSI
48.13
Neutral
STOCH
21.07
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GH, the sentiment is Positive. The current price of 42.66 is below the 20-day moving average (MA) of 44.48, above the 50-day MA of 41.17, and above the 200-day MA of 31.32, indicating a neutral trend. The MACD of -0.29 indicates Positive momentum. The RSI at 48.13 is Neutral, neither overbought nor oversold. The STOCH value of 21.07 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GH.

Guardant Health Risk Analysis

Guardant Health disclosed 69 risk factors in its most recent earnings report. Guardant Health reported the most risks in the “Finance & Corporate” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Guardant Health Peers Comparison

Overall Rating
UnderperformOutperform
Sector (49)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$8.23B101.802.63%0.62%-72.32%
68
Neutral
$19.35B-15.93%56.75%59.77%
GHGH
53
Neutral
$5.12B312.48%31.04%16.91%
53
Neutral
$8.83B-42.83%10.37%-389.98%
51
Neutral
$951.44M-15.85%12.15%61.33%
49
Neutral
$7.05B0.34-55.09%2.46%25.27%-3.43%
49
Neutral
$13.45B-51.54%-2.93%-4.69%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GH
Guardant Health
42.66
24.20
131.09%
EXAS
Exact Sciences
47.63
-8.64
-15.35%
ILMN
Illumina
85.69
-45.63
-34.75%
MYGN
Myriad Genetics
10.34
-12.60
-54.93%
QGEN
Qiagen
38.55
-5.43
-12.35%
NTRA
Natera
147.92
57.70
63.95%

Guardant Health Earnings Call Summary

Earnings Call Date: Feb 20, 2025 | % Change Since: -10.00% | Next Earnings Date: May 7, 2025
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue growth, significant product upgrades, and successful cost reductions, indicating a positive trajectory for Guardant Health. However, litigation expenses and challenges with NCCN guidelines presented some obstacles. Overall, the positive developments outweighed the lowlights.
Highlights
Record Revenue Growth
Q4 2024 revenue grew 30% year-over-year to $202 million, bringing total full year revenue to $739 million, an increase of 31% year-over-year.
Clinical Revenue and Volume Surge
Clinical revenue grew 34% year-over-year, with total oncology clinical volumes increasing 24% in Q4 and 20% for the full year.
Major Product Upgrades
Guardant360 Test upgraded to the Smart Liquid Biopsy platform, expanding genomic markers and improving detection sensitivity by a factor of 10.
Significant ASP Improvement
Guardant360 ASP increased from $2,750 to $3,000, achieving a target four years ahead of schedule due to reimbursement wins.
Shield FDA Approval and Medicare Coverage
Shield became the first FDA-approved and Medicare-covered blood test for CRC screening, with a Medicare price of $920 and potential increase to $1,495.
Cost Reductions and Financial Health
Reveal achieved more than 50% reduction in COGS, and the company ended the year with approximately $944 million in cash, expecting cash flow break-even by 2028.
Lowlights
Litigation Expenses Impact
Significant litigation expenses related to a false advertising trial affected non-GAAP operating expenses, which exceeded guidance.
NCCN Guidelines Concerns
NCCN recommended against surveillance, posing challenges for the adoption of Reveal.
Shield Sales Force Expansion Challenges
Sales force expansion is back-end loaded due to late hiring, affecting the timeline for productivity contributions.
Company Guidance
During the Guardant Health Q4 2024 earnings call, management provided guidance indicating a strong year ahead. The company expects total revenue for 2025 to range between $850 million and $860 million, representing a 15% to 16% growth compared to 2024. This guidance excludes a $22 million non-recurring out-of-period revenue upside in 2024, implying an adjusted growth of 19% to 20%. Oncology revenue is forecasted to grow approximately 15% year-over-year, excluding the non-recurring upside, with clinical volume growth expected at around 25%. The biopharma and data segment is anticipated to see low double-digit growth, while screening revenue from Shield is projected between $25 million and $30 million, driven by 45,000 to 50,000 tests. The company also plans for full-year non-GAAP gross margins of 62% to 63% and aims to reduce free cash flow burn to between $225 million and $235 million, with a focus on maintaining their screening cash burn at approximately $200 million.

Guardant Health Corporate Events

Business Operations and StrategyFinancial Disclosures
Guardant Health Reports Revenue Growth Amid Cash Flow Losses
Neutral
Jan 13, 2025

Guardant Health announced its preliminary, unaudited results for the fourth quarter and full year 2024, reporting a 31% increase in annual revenue driven by strong clinical and biopharma sales. Despite this growth, the company reported a negative free cash flow of $275 million for the full year and cited its strategic focus on expanding its commercial infrastructure following the successful launch of the Shield test, positioning itself for continued growth in the oncology sector.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.