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Exact Sciences Corp. (EXAS)
NASDAQ:EXAS

Exact Sciences (EXAS) AI Stock Analysis

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Exact Sciences

(NASDAQ:EXAS)

53Neutral
Exact Sciences shows promising revenue growth and positive developments like new FDA approvals and international expansion. However, profitability challenges and negative technical indicators weigh down the score. The earnings call provided a positive sentiment, but the financial performance and technical analysis suggest caution.
Positive Factors
Financial Incentives
Inclusion in quality measures marks an important milestone because it gives doctors and health systems a financial incentive to start prescribing Cologuard Plus.
Investment Opportunity
EXAS trades at a discount compared to peers, presenting an attractive investment opportunity.
Revenue Expectations
The launch of Cologuard Plus is expected to drive upside to revenue expectations.
Negative Factors
Performance Concerns
Performance questions linger for CRC blood tests with a 45% miss rate on stage 1 and a 10% false positive rate.
Revenue Estimate Reduction
Lowering the 2025 revenue estimate to $3.040 billion from $3.065 billion and Adjusted EBITDA to $415 million from $541 million.
Seasonal Weakness
1Q tends to be seasonally weak due to lower patient care utilization during the holidays and inclement weather, which can also reduce wellness visits.

Exact Sciences (EXAS) vs. S&P 500 (SPY)

Exact Sciences Business Overview & Revenue Model

Company DescriptionExact Sciences Corporation provides cancer screening and diagnostic test products in the United States and internationally. The company offers Cologuard, a non-invasive stool-based DNA screening test to detect DNA and hemoglobin biomarkers associated with colorectal cancer and pre-cancer. It also provides Oncotype DX, a gene expression tests for breast, prostate, and colon cancers; Oncotype Test, a tissue test delivering tumor profiling to aid therapy selection for patients with advanced, metastatic, refractory, or recurrent cancer; Oncotype DX AR-V7 Nucleus Detect Test, a liquid-based test for advanced stage prostate cancer; Oncomap ExTra, that provides a complete biological picture of certain refractory, rare, or aggressive cancers; and Covid-19 testing services. The company's pipeline products focus on enhancing the Cologuard test's performance characteristics and developing blood and other fluid-based tests. It has license agreements with MAYO Foundation for Medical Education and Research; and Hologic, Inc. Exact Sciences Corporation was incorporated in 1995 and is headquartered in Madison, Wisconsin.
How the Company Makes MoneyExact Sciences generates revenue primarily through the sales of its flagship product, Cologuard, a non-invasive stool-based DNA test for colorectal cancer screening. The company partners with healthcare providers and insurance companies to make Cologuard accessible to a broad patient base, ensuring reimbursement and widespread adoption. Revenue is also driven by the scaling of its laboratory operations and research services. Moreover, Exact Sciences invests in research and development to expand its diagnostic test offerings for other types of cancer, potentially broadening its revenue streams as these products come to market.

Exact Sciences Financial Statement Overview

Summary
Exact Sciences demonstrates strong revenue growth and improving cash flow generation, but faces challenges in profitability and increased leverage. The company must focus on cost management to improve margins and reduce debt levels for enhanced financial stability and sustainable growth.
Income Statement
45
Neutral
Exact Sciences shows strong revenue growth over the years, with Total Revenue increasing from $876.3 million in 2019 to $2.76 billion in 2024. However, the company struggles with profitability, consistently reporting negative Net Income. The Gross Profit Margin is solid but the Net Profit Margin is negative due to high costs and expenses relative to revenue. The EBIT and EBITDA margins are also weak, indicating challenges in operational efficiency.
Balance Sheet
50
Neutral
The company's balance sheet reflects a moderate financial position. The Debt-to-Equity Ratio has increased over time, indicating higher leverage. Stockholders' Equity has decreased, showing declining retained earnings. The Equity Ratio remains reasonable, suggesting that a significant portion of the company is financed by equity. However, the increasing Total Debt is a concern for financial stability.
Cash Flow
55
Neutral
The cash flow statement reveals some positive trends in Free Cash Flow, which turned positive in recent years. Operating Cash Flow has improved, suggesting better cash management. However, the Free Cash Flow to Net Income Ratio is skewed due to negative Net Income figures. The company needs to continue focusing on generating positive cash flows to support growth and reduce reliance on external financing.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
2.76B2.50B2.08B1.77B1.49B
Gross Profit
1.92B1.85B1.51B1.31B1.14B
EBIT
-1.05B-215.01M-577.54M-835.47M-558.35M
EBITDA
-789.33M41.88M-386.74M-617.73M-632.86M
Net Income Common Stockholders
-1.03B-204.15M-623.51M-595.63M-848.53M
Balance SheetCash, Cash Equivalents and Short-Term Investments
1.04B777.64M632.06M1.03B1.84B
Total Assets
5.93B6.47B6.23B6.68B4.93B
Total Debt
2.75B2.55B2.45B2.36B1.46B
Net Debt
2.15B1.95B2.20B2.05B-27.11M
Total Liabilities
3.53B3.33B3.18B3.30B2.10B
Stockholders Equity
2.40B3.15B3.04B3.39B2.82B
Cash FlowFree Cash Flow
74.55M31.93M-438.02M-238.00M72.13M
Operating Cash Flow
210.54M156.12M-223.56M-102.24M136.48M
Investing Cash Flow
-442.15M49.68M74.07M-1.08B-702.04M
Financing Cash Flow
231.87M159.77M76.48M8.47M1.88B

Exact Sciences Technical Analysis

Technical Analysis Sentiment
Negative
Last Price42.55
Price Trends
50DMA
48.77
Negative
100DMA
52.79
Negative
200DMA
55.76
Negative
Market Momentum
MACD
-1.50
Negative
RSI
37.98
Neutral
STOCH
13.19
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For EXAS, the sentiment is Negative. The current price of 42.55 is below the 20-day moving average (MA) of 44.77, below the 50-day MA of 48.77, and below the 200-day MA of 55.76, indicating a bearish trend. The MACD of -1.50 indicates Negative momentum. The RSI at 37.98 is Neutral, neither overbought nor oversold. The STOCH value of 13.19 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for EXAS.

Exact Sciences Risk Analysis

Exact Sciences disclosed 52 risk factors in its most recent earnings report. Exact Sciences reported the most risks in the “Legal & Regulatory” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Exact Sciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (48)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
67
Neutral
$18.10B-19.42%56.75%59.77%
66
Neutral
$8.27B102.992.27%0.66%-75.89%
53
Neutral
$7.90B-37.09%10.37%-389.98%
NENEO
52
Neutral
$1.13B-8.54%11.65%11.33%
49
Neutral
$11.75B-30.11%-2.93%-4.69%
GHGH
49
Neutral
$5.01B-4584.47%31.04%16.91%
48
Neutral
$6.36B1.09-49.92%2.63%17.17%0.95%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
EXAS
Exact Sciences
42.55
-28.78
-40.35%
ILMN
Illumina
74.16
-52.30
-41.36%
QGEN
Qiagen
38.26
-3.23
-7.79%
NEO
NeoGenomics
8.78
-6.07
-40.88%
NTRA
Natera
133.87
38.44
40.28%
GH
Guardant Health
40.58
21.92
117.47%

Exact Sciences Earnings Call Summary

Earnings Call Date: Feb 19, 2025 | % Change Since: -15.71% | Next Earnings Date: May 1, 2025
Earnings Call Sentiment Positive
The earnings call reflected strong financial performance with significant revenue and EBITDA growth, especially in the Screening segment. The company highlighted major achievements like FDA approval for Cologuard Plus and strong international expansion in Precision Oncology. However, the call also addressed challenges such as a substantial non-cash impairment charge related to the Thrive acquisition and modest growth in Precision Oncology. Overall, the positive aspects of revenue growth, new product launches, and strategic advancements outweigh the lowlights, indicating a positive sentiment.
Highlights
Strong Revenue Growth
Fourth quarter revenue grew 10% with a 14% increase in Screening revenue to $553 million. Precision oncology revenue increased slightly to $161 million.
Significant EBITDA Improvement
Adjusted EBITDA increased 52% to $75 million. Adjusted EBITDA margin expanded nearly 300 basis points.
FDA Approval and Medicare Pricing for Cologuard Plus
Secured FDA approval and Medicare pricing for Cologuard Plus, a next-generation colon cancer screening test, with a Medicare price of $592.
Positive Outlook for 2025
Guidance for 2025 anticipates total revenue between $3.025 billion and $3.085 billion, with 11% total revenue growth, including 13% in Screening.
Recognition as a Great Place to Work
Exact Sciences was recognized as a great place to work for the sixth consecutive year.
Expansion in Precision Oncology
Strong double-digit growth internationally in Precision Oncology, leveraging the Oncotype DX brand.
Lowlights
Non-Cash Impairment Charge
Recognized an $830 million non-cash impairment charge related to the Thrive acquisition, reflecting changes in expected reimbursement.
Reclassification of Costs
Costs related to customer care were reclassified from G&A to sales and marketing, impacting financial statements.
Modest Growth in Precision Oncology
Precision oncology revenue only increased slightly, indicating slower growth compared to other segments.
External Factors Affecting Thrive Acquisition
The write-down of the Thrive acquisition was influenced by external factors, such as expected reimbursement outlined in recent legislation.
Company Guidance
During the Exact Sciences Fourth Quarter 2024 Earnings Call, the company provided guidance for 2025, projecting total revenue between $680 million and $695 million for Q1, and between $3.025 billion and $3.085 billion for the full year. Screening revenue is expected to be between $520 million and $530 million for Q1, and $2.35 billion to $2.39 billion for the year. Precision Oncology revenue is forecasted to be between $160 million and $165 million for Q1, and $675 million to $695 million for the full year. Adjusted EBITDA for 2025 is expected to be between $410 million and $440 million, with an anticipated 220 basis point expansion in adjusted EBITDA margin. The company also highlighted key growth drivers including a 13% increase in Screening revenue, supported by the launch of Cologuard Plus, and a 5% growth in Precision Oncology, with strong international performance of Oncotype DX.

Exact Sciences Corporate Events

Product-Related AnnouncementsPrivate Placements and FinancingFinancial Disclosures
Exact Sciences Boosts Finances and Plans New Launches
Positive
Jan 13, 2025

Exact Sciences Corp. announced the signing of a new $500 million revolving credit agreement, replacing its previous credit arrangement, to enhance working capital and corporate operations. The company also reported strong preliminary financial results for the fourth quarter of 2024, with a 10% revenue increase compared to the previous year, and plans to launch three new cancer tests in 2025, which is expected to bolster its market position and advance its mission in cancer diagnostics.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.