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Dyadic International (DYAI)
NASDAQ:DYAI
US Market

Dyadic International (DYAI) AI Stock Analysis

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Dyadic International

(NASDAQ:DYAI)

46Neutral
Dyadic International's overall score reflects significant financial challenges, notably ongoing losses and negative cash flows. While strategic partnerships and revenue growth are positive, they are offset by high leverage and operational inefficiencies. The stock's technical indicators suggest weak momentum, and its valuation remains unattractive due to unprofitability. The earnings call provides some optimism about future growth, but near-term challenges persist.

Dyadic International (DYAI) vs. S&P 500 (SPY)

Dyadic International Business Overview & Revenue Model

Company DescriptionDyadic International (DYAI) is a biotechnology company that focuses on developing and commercializing biopharmaceuticals and bio-based products using its proprietary C1 gene expression platform. This platform is designed to enable the efficient and cost-effective production of biologic products, including vaccines, antibodies, and enzymes, across various industries such as healthcare, agriculture, and industrial enzymes.
How the Company Makes MoneyDyadic International generates revenue through licensing its C1 gene expression technology to pharmaceutical and biotechnology companies. These partnerships often involve upfront payments, milestone payments, and royalties based on the commercial success of products developed using the C1 platform. The company also engages in research and development collaborations, where it provides its expertise and technology in exchange for funding. Additionally, Dyadic may generate revenue through the sale of its proprietary enzymes and other bio-based products developed using its platform.

Dyadic International Financial Statement Overview

Summary
Dyadic International faces significant financial challenges, including negative net income and cash flows, despite some revenue growth. The company's high leverage and operational inefficiencies pose risks, although maintaining liquidity through cash reserves is a positive aspect.
Income Statement
30
Negative
Dyadic International has shown some revenue growth over the years, with a 20.6% increase from 2023 to 2024. However, the company has consistently reported negative net income, leading to negative net profit margins. The EBIT and EBITDA margins are also negative, indicating ongoing operational challenges.
Balance Sheet
45
Neutral
The company's debt-to-equity ratio has increased significantly in 2024, indicating higher leverage and potential financial risk. The equity ratio has decreased over the years, reflecting a lower proportion of equity financing. However, the company maintains a reasonable amount of cash and short-term investments, providing some liquidity cushion.
Cash Flow
40
Negative
Operating cash flows have been negative, reflecting challenges in generating cash from operations. Free cash flow has also remained negative, though there was a notable decrease in the cash outflow in 2024 compared to previous years. The operating cash flow to net income ratio indicates a gap between reported earnings and cash generation, which may concern investors.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
3.50M2.90M2.93M2.40M1.60M
Gross Profit
2.30M922.96K807.11K459.39K176.99K
EBIT
-5.90M-8.23M-10.12M-14.73M-10.03M
EBITDA
-5.90M-8.19M-10.07M-13.07M-10.19M
Net Income Common Stockholders
-5.81M-6.80M-9.37M-12.92M-9.33M
Balance SheetCash, Cash Equivalents and Short-Term Investments
9.26M7.26M12.64M20.26M29.09M
Total Assets
9.93M8.22M13.71M21.30M30.07M
Total Debt
5.07M136.93K0.000.000.00
Net Debt
-1.44M-6.38M-5.79M-15.75M-20.64M
Total Liabilities
7.46M2.34M2.63M2.91M1.63M
Stockholders Equity
2.47M5.88M11.09M18.39M28.45M
Cash FlowFree Cash Flow
-3.97M-6.73M-8.08M-11.28M-6.57M
Operating Cash Flow
-3.97M-6.73M-8.08M-11.28M-6.57M
Investing Cash Flow
-1.88M7.45M-2.37M5.22M22.12M
Financing Cash Flow
5.85M0.00543.59K1.23M255.47K

Dyadic International Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.21
Price Trends
50DMA
1.38
Negative
100DMA
1.51
Negative
200DMA
1.39
Negative
Market Momentum
MACD
-0.05
Negative
RSI
39.43
Neutral
STOCH
35.38
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DYAI, the sentiment is Negative. The current price of 1.21 is below the 20-day moving average (MA) of 1.27, below the 50-day MA of 1.38, and below the 200-day MA of 1.39, indicating a bearish trend. The MACD of -0.05 indicates Negative momentum. The RSI at 39.43 is Neutral, neither overbought nor oversold. The STOCH value of 35.38 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for DYAI.

Dyadic International Risk Analysis

Dyadic International disclosed 41 risk factors in its most recent earnings report. Dyadic International reported the most risks in the “Finance & Corporate” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Dyadic International Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$40.93M10.83-89.62%-71.68%-397.61%
51
Neutral
$5.20B3.26-40.34%2.93%17.68%1.94%
46
Neutral
$36.41M-139.16%20.58%15.90%
34
Underperform
$30.39M-38.49%1773.18%19.16%
34
Underperform
$39.58M-49.69%38.98%
29
Underperform
$6.91M-123.28%650.00%89.72%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DYAI
Dyadic International
1.21
-0.29
-19.33%
IBIO
Ibio
0.76
-1.14
-60.00%
SPRO
Spero Therapeutics
0.73
-0.69
-48.59%
BRNS
Barinthus Biotherapeutics
0.82
-1.69
-67.33%
ANTX
AN2 Therapeutics, Inc.
1.27
-1.13
-47.08%

Dyadic International Earnings Call Summary

Earnings Call Date: Mar 26, 2025 | % Change Since: -9.02% | Next Earnings Date: May 8, 2025
Earnings Call Sentiment Positive
The earnings call highlighted Dyadic's strong revenue growth, successful strategic partnerships, and advancements in product development, marking significant progress towards commercialization. However, increased expenses and a delayed timeline for product launches present challenges. Overall, the call reflects a positive outlook with some caution due to timing and cost-related issues.
Highlights
Strong Revenue Performance
Dyadic delivered strong revenue performance in 2024, including $1.9 million in milestone and license payments, driven by products that do not require clinical trials for commercialization.
Successful Strategic Partnerships
Dyadic established significant partnerships with CEPI, Gates Foundation, and other organizations, securing a $4.5 million grant from CEPI and a $3 million grant from the Gates Foundation for various development projects.
Increased Cash Reserves
Cash, cash equivalents, and investment-grade securities increased to approximately $9.3 million as of December 31, 2024, up from $7.3 million the previous year.
Decrease in Net Loss
Net loss for the year ended December 31, 2024, was approximately $5.809 million, compared to a net loss of $6.795 million for the previous year.
Advancements in Alternative Protein Products
Progress in developing and commercializing alternative protein products, such as recombinant human serum albumin and transferrin, which are on track for commercial launch.
Lowlights
Increased G&A Expenses
General and administrative expenses for 2024 increased to approximately $6.135 million compared to $5.817 million the previous year, due to business development and investor relation expenses.
Delayed Commercialization Timeline
While progress is being made, commercialization of certain products like recombinant human serum albumin and DNase I is anticipated in 2025, indicating a longer timeline to revenue generation.
Company Guidance
In Dyadic International's year-end 2024 conference call, the company highlighted its strategic focus on near-term product commercialization and technology licensing, which has driven strong revenue performance, including $1.9 million in milestone and license payments. The company emphasized its dual-track strategy of commercializing non-pharmaceutical products while building a robust biopharmaceutical pipeline, supported by partnerships with organizations such as CEPI, the Gates Foundation, and Fondazione Biotecnopolo di Siena. Key product developments include recombinant human serum albumin, transferrin, and DNase I, with a commercial launch of recombinant human serum albumin expected in early 2025. Financially, Dyadic reported a revenue increase to $3.495 million for 2024, with a net loss reduced to $5.809 million from the previous year. The company's strategic priorities for 2025 include launching its first commercial products, expanding strategic partnerships, and leveraging its C1 and Dapavas platforms to meet the growing demand for affordable and efficient biomanufacturing technologies.

Dyadic International Corporate Events

Private Placements and FinancingBusiness Operations and Strategy
Dyadic International Secures $4.5M for Vaccine Development
Positive
Mar 20, 2025

On March 20, 2025, Dyadic International announced a $4.5 million funding award from CEPI to accelerate the development of protein-based vaccines using its C1 fungus technology. The initiative aims to reduce vaccine development timelines significantly, potentially enabling vaccines to enter Phase 1 trials in just 35 days compared to the traditional four to six months. This approach could also lower production costs and increase accessibility, particularly in regions with less established manufacturing infrastructure, aligning with the global 100 Days Mission to expedite vaccine readiness against pandemic threats.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.