CompetitionEmerging therapies with competitive risk/benefit profiles, such as PTC’s sepiapterin, could pose a competitive threat to Palynziq in the market.
Investor PerceptionThe company is executing toward its long-term goals while working to convince skeptical investors of its opportunities and under-appreciated strengths.
Safety ConcernsThere is uncertainty about safety results due to the existing black-box warning for Palynziq, which could affect investor perception.