Clinical Trial ResultsActinium Pharmaceuticals presented positive data from the completed Phase 1b combination trial of Actimab-A and CLAG-M in patients with relapsed/refractory acute myeloid leukemia at the Society of Nuclear Medicine & Molecular Imaging Annual Meeting.
Drug EfficacyThe combination of Actimab-A and CLAG-M produced high rates of response, measurable residual disease negativity, bone marrow transplant access, and improved survival outcomes in high-risk patients.
Preclinical DataNew preclinical data demonstrated that combining Actimab-A with a leading menin inhibitor significantly increased cell death and prolonged anti-tumor effects compared to single-agent therapy in xenograft leukemia models.