SKYTROFA Market Position
SKYTROFA achieved a leading position in the U.S. growth hormone market with a 60% year-over-year increase in demand volume in Q3. The product maintains a net value per patient of 3x that of daily growth hormone.
YORVIPATH Launch Preparedness
Ascendis is preparing for the U.S. launch of YORVIPATH, the first FDA-approved treatment for hypoparathyroidism in adults, with a commercial infrastructure 3x the size of SKYTROFA's. The launch is expected to support 200 existing patients and will expand to all adults with chronic hypoparathyroidism by January 2025.
Novo Nordisk Collaboration
Ascendis entered a collaboration with Novo Nordisk for a once-monthly GLP-1 program targeting obesity and type 2 diabetes, expected to be a major market opportunity. The collaboration will include a $100 million upfront payment and tiered royalties.
Financial Strength and Revenue Growth
Ascendis reported a 21% increase in SKYTROFA revenue for the first nine months of 2024, totaling EUR 138.5 million. The company improved its financial position with EUR 626 million in cash and marketable securities.