Regulatory UncertaintyThere is uncertainty on the efficacy of Assembly's programs including ABI-5366, ABI-4334, and ABI-6250, at a level that could potentially support their advancement towards regulatory approvals.
Safety ConcernsUncertainty on the safety and efficacy of Assembly's programs including ABI-5366 and ABI-6250.
Trial RisksKey risks include failed or equivocal trial results, unforeseen safety or tolerability issues, and meaningful delays to expected timelines.