Strong Financial Position and Revenue Growth
Ascendis Pharma ended 2024 with a strong financial position, holding €665 million in cash, including a $100 million upfront payment from Novo Nordisk. Total revenue for 2024 was €363.6 million, with SKYTROFA achieving revenue of around €200 million, a significant increase supported by an 84% volume increase in the U.S.
Successful Launch of YORVIPATH in the U.S.
YORVIPATH, the only FDA-approved treatment for hypothyroidism in adults, has launched in the U.S. and has already shown strong initial demand with 908 patient prescriptions as of February 7, 2025. The product is expected to grow into a multi-billion-dollar product over time.
Positive Developments in Pipeline
TransCon CNP clinical data demonstrated potential as a highly differentiated product for achondroplasia, with plans to submit an NDA for its treatment in Q1 2025. Additionally, a combination treatment with TransCon Growth Hormone is in development.
Expansion Beyond Endocrine Rare Diseases
Ascendis Pharma is expanding its TransCon technology platform beyond endocrine rare diseases, collaborating with Novo Nordisk in metabolic diseases, and forming Eyconis for ophthalmology therapies.