Increased Revenue
Revenue for 2024 was $28.7 million, a significant increase compared to $7.4 million in 2023, primarily from government contracts related to BARDA and non-cash royalty revenue from sales of Inavir in Japan.
Progress in Norovirus Vaccine Development
Initiated a Phase 1 trial for second-generation oral norovirus vaccine constructs, with promising preclinical data indicating potentially more potent responses compared to the first-generation constructs.
Positive Safety Profile
The norovirus oral vaccine candidate demonstrated a benign safety and tolerability profile consistent with previous studies, with no significant differences in adverse events between the vaccine candidate and placebo.
Publication in Science Translational Medicine
Two articles were published on norovirus studies, highlighting the efficiency of the Vaxart platform in generating mucosal antibody responses and supporting immunogenicity in older adults.
Cash Runway Extended
Implemented measures to reduce expenses, including a workforce reduction, and anticipates cash runway into the fourth quarter of 2025.