Successful Launch of O2VARE
In the first full quarter of commercial availability, net sales of O2VARE were $36.6 million in Q4 and $42.3 million for the full year 2024. The launch momentum is strong with more prescriptions dispensed in the first two months of Q1 2025 than in Q4 2024.
Positive Prescriber Adoption
Over 4,600 unique HCPs are prescribing O2VARE, including 55% of 2,500 tier one HCPs. Over 275 HCPs have prescribed O2VARE to more than 20 patients in their practice.
Global Expansion and Regulatory Advances
Nuance Pharma announced the approval of O2VARE in Macau and completed enrollment in its pivotal Phase 3 clinical trial in China. Preparations are underway for potential marketing authorization applications in the EU and UK.
Strong Financial Position
Verona Pharma ended 2024 with $400 million in cash and equivalents, with access to up to $425 million of additional capital through the Oak Creek facility.
Pipeline Progress
Completed Phase 2 clinical trial with glycopyrrolate ALAMA and plans to initiate a Phase 2b trial evaluating a fixed-dose combination of ensifentrine with glycopyrrolate in the second half of 2025.