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Vor Biopharma (VOR)
NASDAQ:VOR
US Market

Vor Biopharma (VOR) AI Stock Analysis

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Vor Biopharma

(NASDAQ:VOR)

33Underperform
Vor Biopharma faces significant financial challenges, with no revenue and ongoing losses. Technical indicators suggest weak market sentiment, and the lack of positive valuation metrics further underscores the risk. Investors should be cautious due to the high financial risk and uncertainty.
Positive Factors
Clinical Progress
Trem-cel continues to demonstrate high engraftment rate, shielding from MYLOTARG on-target toxicity with a broader therapeutic window, and early evidence of improved relapse free survival.
Financial Stability
Vor Biopharma has a sufficient cash position of approximately $91.9M to fund planned operations into the first quarter of 2026.
Regulatory Approval
FDA does not require additional data to start the Phase III trial and agreed with VOR on its design.
Negative Factors
Financial Performance
The company reported no revenues for FY24 and a net loss per share that was worse than consensus estimates.
Market Conditions
Challenging capital markets and negative pressure on the gene/cell therapy sector have led to significant share count dilution.
Stock Price Target
The 12-month price target for the stock has been lowered from $17.50 to $13.00 due to a risk-adjusted net present value analysis.

Vor Biopharma (VOR) vs. S&P 500 (SPY)

Vor Biopharma Business Overview & Revenue Model

Company DescriptionVor Biopharma, Inc., a clinical-stage company, develops engineered hematopoietic stem cell (eHSC) therapies for cancer patients. It is developing VOR33, an eHSC product candidate that is in phase 1/2 to treat acute myeloid leukemia (AML) and other hematological malignancies. The company's VOR33 eHSCs lacks CD33, a protein that is expressed by AML blood cancer cells. The company's eHSCs targeted therapies, such as CAR-Ts, bispecific antibodies, and antibody-drug conjugates provide treatment for blood cancers. Vor Biopharma, Inc. has a collaboration agreement with Akron BioProducts to develop and manufacture cGMP nucleases. The company was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
How the Company Makes MoneyVor Biopharma generates revenue primarily through research and development collaborations, partnerships, and potential future product sales. The company's business model is centered around developing its pipeline of eHSC-based therapies, which are designed to improve the efficacy and safety of existing cancer treatments. Revenue streams may include milestone payments and royalties from strategic partnerships with larger pharmaceutical companies, as well as potential licensing agreements for its proprietary technologies. Additionally, Vor Biopharma may secure funding through government grants or research institutions to support its innovative research initiatives.

Vor Biopharma Financial Statement Overview

Summary
Vor Biopharma shows significant financial strain with zero revenue and consistent losses. The balance sheet indicates declining equity, and cash flow statements reflect persistent cash burn issues, presenting high financial risk.
Income Statement
10
Very Negative
Vor Biopharma has consistently reported zero revenue, indicating a lack of operational income generation. The company has been operating at a loss for several years, with negative EBIT and net income, highlighting significant profitability challenges.
Balance Sheet
35
Negative
The company maintains a moderate debt-to-equity ratio, which suggests limited leverage. However, the continuous decline in stockholders' equity and total assets since 2020 raises concerns about financial stability and sustainability.
Cash Flow
20
Very Negative
Vor Biopharma's free cash flow has been consistently negative, indicating cash burn issues. The operating cash flow is also negative, suggesting operational inefficiencies and an inability to cover costs without external funding.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
0.000.000.000.000.00
Gross Profit
0.00-3.49M-8.96M-4.45M-1.39M
EBIT
-121.19M-126.04M-93.42M-69.02M-43.37M
EBITDA
-121.19M-114.37M-90.89M-67.58M-41.95M
Net Income Common Stockholders
-116.91M-117.86M-90.77M-68.78M-43.34M
Balance SheetCash, Cash Equivalents and Short-Term Investments
91.93M137.18M230.25M207.47M48.54M
Total Assets
142.89M198.13M299.37M242.59M75.91M
Total Debt
31.83M35.66M38.91M18.01M18.29M
Net Debt
-50.12M4.30M-18.79M-101.79M-30.25M
Total Liabilities
46.23M47.40M48.76M26.33M27.64M
Stockholders Equity
96.66M150.72M250.61M216.26M48.27M
Cash FlowFree Cash Flow
-99.89M-101.36M-93.61M-73.04M-40.45M
Operating Cash Flow
-99.66M-100.29M-85.14M-69.14M-36.29M
Investing Cash Flow
96.86M71.01M-94.09M-91.65M-4.16M
Financing Cash Flow
53.39M2.94M117.14M232.91M82.53M

Vor Biopharma Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price0.70
Price Trends
50DMA
0.91
Negative
100DMA
1.05
Negative
200DMA
0.95
Negative
Market Momentum
MACD
-0.05
Negative
RSI
52.02
Neutral
STOCH
75.90
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For VOR, the sentiment is Neutral. The current price of 0.7 is above the 20-day moving average (MA) of 0.66, below the 50-day MA of 0.91, and below the 200-day MA of 0.95, indicating a neutral trend. The MACD of -0.05 indicates Negative momentum. The RSI at 52.02 is Neutral, neither overbought nor oversold. The STOCH value of 75.90 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for VOR.

Vor Biopharma Risk Analysis

Vor Biopharma disclosed 81 risk factors in its most recent earnings report. Vor Biopharma reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Vor Biopharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$5.20B3.26-40.34%2.93%17.68%1.94%
46
Neutral
$104.98M-89.73%-100.00%24.59%
44
Neutral
$105.56M-42.83%48.92%
44
Neutral
$92.77M149.62%-31.04%11.34%
41
Neutral
$110.77M-45.58%71.44%43.22%
38
Underperform
$92.08M-54.09%-100.00%-26.44%
VOVOR
33
Underperform
$87.65M-94.52%2.98%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
VOR
Vor Biopharma
0.76
-0.98
-56.32%
ZNTL
Zentalis Pharmaceuticals
1.50
-10.27
-87.26%
PLRX
Pliant Therapeutics
1.54
-10.36
-87.06%
CCCC
C4 Therapeutics
1.61
-4.86
-75.12%
ELUT
Aziyo Biologics
2.29
-0.60
-20.76%
SNTI
Senti Biosciences
4.43
1.62
57.65%

Vor Biopharma Corporate Events

Executive/Board Changes
Vor Biopharma’s Chief Medical Officer Resigns
Neutral
Apr 3, 2025

On March 31, 2025, Eyal C. Attar, M.D., announced his resignation as Chief Medical Officer of Vor Biopharma Inc., effective April 18, 2025, to pursue a new opportunity. Vor Biopharma plans to enter into a consulting agreement with Dr. Attar for transition services, acknowledging his contributions to the company.

Business Operations and Strategy
Vor Biopharma Approves Stock Option Repricing Strategy
Neutral
Feb 6, 2025

On February 3, 2025, Vor Biopharma’s board approved a stock option repricing to reduce the exercise price of certain options to $1.34 per share, impacting approximately 6.76 million shares. This move aims to motivate and retain employees while avoiding stock dilution or additional cash outlays, with a retention period set until February 3, 2026 or earlier under specific conditions.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.