Twist Bioscience stock analysis
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Twist Bioscience (TWST) Stock Price & Analysis
TWST Stock Chart & Stats
- Day’s Range
- $93.68 - $114.97
- 52-Week Range
- $23.30 - $219.71
- Previous Close
- $122.59
- Volume
- N/A
- Average Volume (3M)
- 2.89M
- Market Cap
- $8.07B
- Enterprise Value
- $12.12B
- Total Cash (Recent Filing)
- $166.84M
- Total Debt (Recent Filing)
- $93.59M
- Price to Earnings (P/E)
- ―
- Beta
- 1.69
- Next Earnings
- Jan 29, 2027 (Est.)
- EPS Estimate
- -0.37
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Sustained Revenue Growth
Sustained double-digit revenue growth and raised annual guidance indicate expanding demand across Twist’s synthetic biology, NGS, and therapeutics offerings. Continued growth can improve operating leverage, support investment in the platform, and strengthen the company’s position with life-science customers over the next several quarters.
Improving Manufacturing Efficiency And Margins
Large improvements in manufacturing cost, waste, turnaround time, and capacity support a more scalable operating model. These efficiencies can help preserve gross-margin gains as revenue expands, increase throughput for complex customer orders, and improve the long-term economics of Twist’s silicon-based DNA platform.
Strengthened Funding Capacity
The capital raise materially expands resources available for research, manufacturing capacity, product development, and working capital. This funding can support execution of Twist’s growth strategy and provide greater flexibility while the company works toward sustainable profitability and broader commercial adoption.
Bears Say
Persistent Cash Burn
Persistent negative operating and free cash flow means the business has not yet funded its operations internally. Continued cash consumption can require reliance on external capital, limit financial flexibility, and make successful execution of the growth plan increasingly dependent on reaching positive operating cash flow.
Profitability Remains Unproven
Despite improving revenue and gross margin, Twist remains substantially unprofitable at both the net income and operating levels. The company’s EBITDA breakeven target is still prospective, so elevated expenses and any slower growth could delay operating leverage and extend the period of losses.
Order Conversion And Competitive Risk
Separation between order activity and recognized revenue can make growth less predictable, particularly for large AI-driven orders. Competitive actions and discounting may also pressure sequencing and protein-business mix or average selling prices, reducing the consistency of revenue conversion and margins.
Twist Bioscience News
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Twist Bioscience Stock Smart Score
Company Description
Twist Bioscience
Twist Bioscience Corporation operates as a leading synthetic biology firm, specializing in the production and sale of products developed from synthesized DNA. The company utilizes a unique DNA synthesis platform that facilitates the creation of artificial DNA by "writing" it directly onto silicon chips. Its extensive product catalog encompasses custom synthetic genes, specialized tools designed for sample preparation, comprehensive antibody libraries essential for pharmaceutical research and development, and advanced applications leveraging DNA for digital data storage. Twist Bioscience has established strategic collaborations with several organizations, including Victorian Clinical Genetic Services, Vivlion GmbH, Kyowa Kirin Pharmaceutical Research, Inc., deepCDR Biologics AG, and Centogene N.V., with the shared goal of innovating advanced sequencing technologies. Furthermore, the company engages in a research alliance with Boehringer Ingelheim International GmbH, where it applies its exclusive antibody libraries to identify and develop therapeutic antibodies against a multitude of targets. The corporation was founded in 2013 and is headquartered in South San Francisco, California.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Emily Marine Leproust
- Employees
- 979
- Website
- www.twistbioscience.com
- Address
- 681 Gateway Boulevard, South San Francisco, CA, 94080, US
Twist Bioscience (TWST) Earnings & Revenues
TWST Company Deck
TWST Earnings Call
Earnings Call SentimentPositive
The call was strongly positive, supported by 28% fourth-quarter revenue growth, 22% full-year growth, gross-margin expansion, positive fourth-quarter adjusted EBITDA, 175% AI drug discovery revenue growth, robust customer and order momentum, strong liquidity and above-20% fiscal 2027 revenue-growth guidance. The principal challenges were the full-year adjusted EBITDA loss, planned investment-related depreciation and manufacturing-cost headwinds, early-stage mRNA revenue, difficulty classifying AI revenue and customer concentration within NGS. Highlights significantly outweighed the lowlights.
View all TWST earnings summariesTWST Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 7 | 3 | 12 |
| Technical Analysis | 5 | 3 | 2 |
| Moving Averages | 2 | 0 | 10 |













