BRACELET-1 Breast Cancer Study Exceeds Expectations
The final data from the BRACELET-1 breast cancer study not only met but exceeded expectations, showing a marked statistically significant near doubling of median overall survival in HR-positive HER2-negative metastatic breast cancer.
Positive Results in Gastrointestinal Tumors
Initial safety and efficacy data in both pancreatic and anal cancers are positive. A 33% objective response rate was reported from the goblet cohort four in relapsed anal cancer, including a complete response lasting more than 15 months.
Promising Business Development and Collaborations
Ongoing business development discussions have been positive, with pelareorep showing potential in breast, pancreatic, and anal cancers. Collaborations with GCAR and PanCAN continue to progress, with a $5 million grant from PanCAN funding goblet cohort five.
Robust Financial Management
As of December 31, 2024, the company reported $15.9 million in cash and cash equivalents, with net cash used in operating activities slightly reduced from the previous year.