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Schrodinger (SDGR)
NASDAQ:SDGR
US Market

Schrodinger (SDGR) AI Stock Analysis

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Schrodinger

(NASDAQ:SDGR)

45Neutral
Schrodinger shows potential with strong software revenue growth and strategic collaborations. However, persistent profitability challenges, negative cash flows, and increased operating losses weigh heavily on its financial outlook. The technical indicators suggest a neutral market position, while valuation is hindered by ongoing losses.
Positive Factors
Customer Retention
Customer retention rate among high-value customers was 100%, and the number of such customers increased from 54 to 61.
Growth Prospects
Optimism remains for further large collaboration announcements as more biopharma companies follow NVS's playbook.
Partnerships
An expanded research collaboration with LLY builds on a previous collaboration, indicating strengthened partnerships.
Revenue Growth
4Q24 software revenue increased 16.0% year-over-year due to increased hosted revenue from large customers.
Negative Factors
Cost Management
Software gross margin decreased to 83% due to higher cost of revenue associated with the predictive toxicology initiative.
Revenue Expectations
Q3 revenues were lower than consensus estimates primarily due to lower than anticipated software contribution.

Schrodinger (SDGR) vs. S&P 500 (SPY)

Schrodinger Business Overview & Revenue Model

Company DescriptionSchrödinger, Inc. is a leading provider of advanced molecular simulations and enterprise software solutions for the pharmaceutical, biotechnology, and materials science sectors. The company leverages its cutting-edge physics-based computational platform to accelerate drug discovery and materials design, offering a suite of software tools for molecular modeling, simulation, and data analysis. Schrödinger's core products include its flagship software platform for drug discovery and development, which is used by scientists and researchers worldwide to predict the properties and behavior of molecules with high accuracy.
How the Company Makes MoneySchrödinger generates revenue through multiple streams, primarily from software licensing, drug discovery collaborations, and materials science research partnerships. The company's software is licensed to pharmaceutical and biotechnology companies, academic institutions, and government laboratories, providing them with powerful tools for molecular modeling and simulations. Schrödinger also engages in strategic collaborations with pharmaceutical companies to co-develop novel therapeutics, sharing the potential commercial success of these projects. In addition, the company partners with materials science entities to apply its simulation technology to develop innovative materials, further diversifying its revenue streams. These collaborations often include milestone payments and royalties based on the success of the projects.

Schrodinger Financial Statement Overview

Summary
Schrodinger exhibits growth in revenue but struggles with profitability and cash flow generation. The company's increasing leverage and negative cash flows pose potential risks to its financial stability. Persistent losses and cash flow issues require strategic attention to improve financial health.
Income Statement
35
Negative
Schrodinger's revenue has shown a positive trend with a consistent increase from 2019 to 2023. However, the company has faced continuous net losses, with significant negative EBIT and EBITDA margins, indicating challenges in achieving profitability. The gross profit margin improved slightly in recent years, but the negative net profit margin remains a concern for financial stability.
Balance Sheet
45
Neutral
The balance sheet shows a relatively stable equity position, although the debt-to-equity ratio has increased over time, reflecting higher leverage. The company has maintained a positive equity ratio, indicating a moderate level of financial health. However, the increasing liabilities and decreasing equity could pose long-term risks if not managed effectively.
Cash Flow
30
Negative
Cash flow analysis reveals a concerning trend with consistently negative operating and free cash flows, indicating that the company struggles to generate cash from its core operations. The negative free cash flow to net income ratio further highlights this issue. Positive financing cash flows indicate reliance on external financing, which might not be sustainable long-term.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
207.54M216.67M180.96M137.93M108.09M
Gross Profit
132.08M140.69M101.02M65.62M63.47M
EBIT
-209.30M-177.45M-149.12M-111.44M-60.92M
EBITDA
-209.30M-171.90M-142.47M-108.60M-57.26M
Net Income Common Stockholders
-187.12M40.72M-149.19M-101.22M-26.64M
Balance SheetCash, Cash Equivalents and Short-Term Investments
352.12M463.00M451.09M576.48M642.69M
Total Assets
823.23M802.96M688.59M756.49M746.26M
Total Debt
117.83M127.88M116.49M79.87M11.76M
Net Debt
-29.50M-27.43M26.02M-40.40M-190.53M
Total Liabilities
401.78M254.40M240.68M199.40M122.24M
Stockholders Equity
421.44M548.56M447.89M557.07M624.01M
Cash FlowFree Cash Flow
-164.68M-150.14M-127.70M-77.84M14.22M
Operating Cash Flow
-157.37M-136.73M-119.68M-70.67M16.76M
Investing Cash Flow
148.84M193.03M90.02M-16.81M-381.72M
Financing Cash Flow
10.12M9.05M2.11M7.95M541.27M

Schrodinger Technical Analysis

Technical Analysis Sentiment
Negative
Last Price19.96
Price Trends
50DMA
22.98
Negative
100DMA
21.65
Negative
200DMA
20.72
Negative
Market Momentum
MACD
-0.52
Positive
RSI
39.05
Neutral
STOCH
3.63
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SDGR, the sentiment is Negative. The current price of 19.96 is below the 20-day moving average (MA) of 21.69, below the 50-day MA of 22.98, and below the 200-day MA of 20.72, indicating a bearish trend. The MACD of -0.52 indicates Positive momentum. The RSI at 39.05 is Neutral, neither overbought nor oversold. The STOCH value of 3.63 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SDGR.

Schrodinger Risk Analysis

Schrodinger disclosed 88 risk factors in its most recent earnings report. Schrodinger reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Schrodinger Peers Comparison

Overall Rating
UnderperformOutperform
Sector (49)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
$8.67B107.272.27%0.66%
64
Neutral
$126.52B-3.15%11.64%-114.72%
52
Neutral
$5.67B-31.26%104.04%87.80%
49
Neutral
$6.85B0.81-52.91%2.50%17.48%1.17%
48
Neutral
$2.34B-61.89%32.00%-6.86%
45
Neutral
$1.46B-38.58%-4.21%-544.81%
41
Neutral
$2.15B-37.40%-100.00%-144.79%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SDGR
Schrodinger
19.96
-6.37
-24.19%
QGEN
Qiagen
39.85
-2.63
-6.19%
VRTX
Vertex Pharmaceuticals
492.69
72.21
17.17%
BPMC
Blueprint Medicines
88.72
-7.70
-7.99%
DNLI
Denali Therapeutics
14.78
-5.78
-28.11%
RXRX
Recursion Pharmaceuticals
5.81
-3.56
-37.99%

Schrodinger Earnings Call Summary

Earnings Call Date: Feb 26, 2025 | % Change Since: -8.02% | Next Earnings Date: Apr 30, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted significant growth in software revenue and strategic collaborations, indicating positive operational momentum. However, the company faced challenges with increased operating losses and a decline in drug discovery revenue. While the progress in clinical programs and high customer retention are promising, financial strains and increased costs present challenges.
Highlights
Record-Breaking Software Revenue Growth
Software revenue reached $180 million in 2024, representing a growth of over 13% year-over-year. Fourth quarter software revenue grew 16% to $80 million.
Successful Collaborations and Partnerships
Schrödinger established a new drug discovery collaboration and expanded a software agreement with Novartis. The company also expanded existing partnerships with Otsuka and Lilly.
Clinical Program Advancements
Progress in clinical programs, including the initiation of a Phase 1 study for SGR-3515 and anticipated clinical data releases for SGR-1505, SGR-2921, and SGR-3515 in 2025.
High Customer Retention
100% customer retention for those with annual contract value (ACV) of at least $500,000, and significant growth in customers with ACV over $5 million.
Lowlights
Increased Operating Loss
Operating loss for 2024 was $209 million, compared to $177 million in 2023, with a net loss of $187 million for the year.
Decline in Drug Discovery Revenue
Drug discovery revenue dropped from $58 million in 2023 to $27 million in 2024, attributed to the impact of non-recurring milestones.
Increased Cost of Revenue
Overall cost of revenue increased by 46% in Q4 2024 compared to Q4 2023, affecting gross margin, which declined from 77.6% to 72.6%.
Cash Position and Usage
Net cash used in operating activities was $157 million in 2024, an increase from $137 million in 2023, with a cash balance of $367 million at year-end.
Company Guidance
During the call, Schrödinger provided guidance for 2025, emphasizing plans to accelerate software business growth and advance drug discovery programs. The company anticipates software revenue growth between 10% and 15% and drug discovery revenue in the range of $45 million to $50 million. Hosted contracts are expected to account for a larger portion of the revenue, slightly reducing the fourth-quarter concentration. The software gross margin is projected to be 74% to 75%, down from 79.5% in 2024, due to the increased contribution from the predictive toxicology initiative. Operating expenses are anticipated to grow by less than 5% in 2025, with net cash used in operations expected to be lower than in 2024. Schrödinger's strong performance in key metrics, such as customer retention and annual contract values, underpins its optimistic outlook for the upcoming year.
Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.