Clinical TrialsThe EryDex P3 study stems from a prior miss in another P3 (ATTeST) while with EryDel, indicating previous challenges in achieving primary endpoints.
Research ChallengesThe ATTeST study missed on the primary endpoint of intent-to-treat modified International Cooperative Ataxia Rating Scale.
Study DiscontinuationsThree patients were discontinued from the study, with one patient experiencing a serious adverse event of B-cell lymphoma and two others experiencing treatment-emergent adverse events such as pyrexia, tachycardia, pain, and pruritus.