Clinical Trial SuccessTaletrectinib at 600mg QD demonstrated a 91% confirmed ORR (cORR)—78.6% of responders had at least a 24-month duration of response—and a mPFS that was not yet reached in TKI-naive ROS1+ NSCLC patients.
Financial PositionNuvation Bio ended 1Q24 with $597M in cash, cash equivalents, and marketable securities, which should provide an operational runway through 2028.
Regulatory ApprovalTaletrectinib has recently been granted orphan drug designation by the FDA for the treatment of ROS1, NTRK, ALK, LTK, ACK1, or DDR1-positive NSCLC.