Successful Enrollment and Study Progress
Nektar completed enrollment for two Phase 2b studies in atopic dermatitis (REZOLVE-AD) and alopecia areata (REZOLVE-AA) on schedule, demonstrating strong interest from patients and physicians. Topline data for atopic dermatitis is expected in Q2 2025 and for alopecia areata in Q4 2025.
Financial Stability
Nektar ended 2024 with $269 million in cash and investments and a cash runway extending into Q4 2026, ensuring financial stability for ongoing and future projects.
Fast Track Designation for REZPEG
REZPEG received Fast Track designation from the FDA for the treatment of moderate to severe atopic dermatitis, facilitating a closer collaboration with the agency for future development plans.
Collaboration with TrialNet for Type 1 Diabetes Study
Nektar partnered with TrialNet to conduct a Phase 2 trial of REZPEG in type 1 diabetes, aiming to preserve insulin-producing beta cells and improve patient outcomes.
Advancement in Preclinical Programs
The company is advancing its TNFR2 agonist antibody program, NKTR-0165, with plans for an IND submission in H2 2025, and developing a pipeline of bispecific molecules pairing TNFR2 agonism with other targets.