Positive Initial Clinical Data for Emi-Le
Mersana reported positive initial clinical data for its lead Dolasynthen ADC, Emi-Le, and started the expansion portion of its Phase I trial. The company was also granted an additional Fast Track designation for a portion of the breast cancer population.
Strong Safety Profile of Emi-Le
Emi-Le demonstrated a differentiated safety profile with common treatment-related adverse events being manageable and without dose-limiting neutropenia, neuropathy, ocular toxicity, interstitial lung disease, or thrombocytopenia.
Confirmed Objective Responses
Confirmed objective responses were observed in all enrolled tumor types, including triple-negative breast cancer, with a 23% objective response rate in high B7-H4 expression patients.
Collaboration Revenue Increase
Collaboration revenue for the fourth quarter of 2024 was $16.4 million, up from $10.7 million in the same period in 2023, due to increased collaboration revenue under agreements with J&J, Merck KGaA, and GSK.
Reduced Net Loss
Mersana's net loss for the fourth quarter of 2024 was $14.1 million, compared to a net loss of $19.5 million for the same period in 2023, reflecting operational efficiencies.