Strong Financial Performance
Mirum Pharmaceuticals reported total net product sales of $336.4 million for 2024, exceeding the upper-end of their revised guidance range. This represents a significant increase from $178.9 million in 2023.
LIVMARLI Sales Growth
LIVMARLI achieved total net product sales of $213.3 million in 2024, representing a 50% increase compared to 2023. The growth was driven by increased demand in Alagille syndrome and PFIC.
New Product Approval
The FDA approved CTEXLI for cerebrotendinous xanthomatosis (CTX) in adults, providing a new treatment option with seven years of exclusivity.
Pipeline Advancements
Positive interim results for Volixibat in VISTAS PSC and VANTAGE PBC studies led to breakthrough designation in PBC. Additionally, the Phase 3 EXPAND study of LIVMARLI in cholestatic pruritus was initiated.
Strong Cash Position
Mirum ended 2024 with $293 million in cash, cash equivalents, and investments, and the company was cash flow positive for the year.