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Lantern Pharma, Inc. (LTRN)
NASDAQ:LTRN
US Market

Lantern Pharma (LTRN) AI Stock Analysis

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Lantern Pharma

(NASDAQ:LTRN)

43Neutral
Lantern Pharma's stock score is constrained by its significant financial challenges, including a lack of revenue and negative cash flows. While technical indicators suggest potential for a short-term rebound, the company's unattractive valuation and need for substantial additional funding present risks. Strategic advancements in AI-driven oncology drug development provide some long-term promise, but financial sustainability remains a critical concern.

Lantern Pharma (LTRN) vs. S&P 500 (SPY)

Lantern Pharma Business Overview & Revenue Model

Company DescriptionLantern Pharma Inc., a clinical stage biotechnology company, focuses on artificial intelligence, machine learning, and genomic data to streamline the drug development process. Its advanced drug candidate is LP-100, which is in phase II clinical trials to treat metastatic, castration-resistant, and prostate cancer. The company also develops LP-300 as a combination therapy for non or never-smokers with non-small cell lung cancer adenocarcinoma. In addition, its preclinical development drug candidate is LP-184, an alkylating agent that damages DNA in cancer cells that overexpress certain biomarkers or that harbor mutations in DNA repair pathways. Further, the company operates ADC program, an antibody drug conjugate therapeutic approach for cancer treatment. Additionally, the company's artificial intelligence platform RADR uses big data analytics and machine learning for combining molecular data. The company was incorporated in 2013 and is headquartered in Dallas, Texas.
How the Company Makes MoneyLantern Pharma generates revenue primarily through the development and commercialization of its drug candidates. The company uses its proprietary RADR platform to identify biomarkers and genetic signatures that can predict patient response to its drug candidates, thereby reducing time and cost associated with drug development. Revenue streams include out-licensing partnerships, collaborations with pharmaceutical companies, and potentially, future sales of approved drugs. These partnerships often involve milestone payments, royalties, and shared development costs, which are significant contributors to the company's earnings. As Lantern Pharma advances its drug pipeline and secures additional partnerships, these factors are expected to drive financial growth.

Lantern Pharma Financial Statement Overview

Summary
Lantern Pharma's financial health shows significant challenges, primarily due to its inability to generate revenue and increasing operational losses. While its balance sheet is relatively robust with low debt levels, the cash flow situation raises concerns about long-term viability and the need for additional financing if operational metrics do not improve.
Income Statement
20
Very Negative
Lantern Pharma has consistently reported zero revenue, indicating a pre-revenue stage or significant challenges in generating sales. The company's net losses have increased substantially over the years, reflecting mounting operational challenges. The EBIT and EBITDA margins are negative due to high operational expenses without corresponding revenue, undermining profitability prospects.
Balance Sheet
60
Neutral
The company maintains a strong equity position relative to its assets, with a high equity ratio, reflecting financial stability. The debt-to-equity ratio is low, indicating minimal reliance on debt financing, which reduces financial risk. However, the consistent increase in liabilities and decreasing cash reserves could affect future liquidity and operational capacity.
Cash Flow
30
Negative
Lantern Pharma exhibits negative operating and free cash flows, indicating cash burn without revenue inflow. Despite substantial financing inflows in prior years, the inability to generate positive cash flows from operations is concerning. The lack of free cash flow growth highlights potential sustainability challenges.
Breakdown
TTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
261.05K0.000.000.000.000.00
Gross Profit
170.47K0.00-174.84K-154.68K-97.42K-3.39K
EBIT
-21.20M-22.22B-17.88M-14.43M-12.59M-5.91M
EBITDA
-21.18M-22.22B-15.79M-14.42M-12.27M-5.90M
Net Income Common Stockholders
-19.09M-20.78B-15.96M-14.09M-12.30M-5.91M
Balance SheetCash, Cash Equivalents and Short-Term Investments
55.20M24.01B41.30M55.20M70.73M19.23M
Total Assets
58.84M25.57B43.65M58.84M73.95M20.36M
Total Debt
52.89K243.66M234.47K52.89K204.95K108.50K
Net Debt
-37.15M-7.27B-21.70M-37.15M-51.32M-19.12M
Total Liabilities
2.80M4.38B2.74M2.80M2.38M660.84K
Stockholders Equity
56.04M21.19B40.91M56.04M71.57M19.70M
Cash FlowFree Cash Flow
-17.24M-17.81B-14.37M-12.80M-10.61M-5.67M
Operating Cash Flow
-17.23M-17.81B-14.35M-12.77M-10.59M-5.65M
Investing Cash Flow
178.29K3.37B-930.21K179.27K-19.53M-16.14K
Financing Cash Flow
-433.29K66.71M-500.00K63.42M23.66M

Lantern Pharma Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.99
Price Trends
50DMA
4.11
Negative
100DMA
3.83
Negative
200DMA
3.89
Negative
Market Momentum
MACD
-0.16
Positive
RSI
34.43
Neutral
STOCH
10.94
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LTRN, the sentiment is Negative. The current price of 2.99 is below the 20-day moving average (MA) of 3.60, below the 50-day MA of 4.11, and below the 200-day MA of 3.89, indicating a bearish trend. The MACD of -0.16 indicates Positive momentum. The RSI at 34.43 is Neutral, neither overbought nor oversold. The STOCH value of 10.94 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for LTRN.

Lantern Pharma Risk Analysis

Lantern Pharma disclosed 72 risk factors in its most recent earnings report. Lantern Pharma reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Lantern Pharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (48)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
48
Neutral
$6.35B1.19-46.87%2.63%17.16%1.34%
45
Neutral
$2.55B-82.95%-22.34%
43
Neutral
$32.25M-66.93%-31.16%
42
Neutral
$86.28M-54.21%-78.55%-0.92%
39
Underperform
$83.27M-337.30%45.30%45.67%
29
Underperform
$67.55M-155.76%25.77%32.56%
26
Underperform
$9.76M-110.77%18.61%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LTRN
Lantern Pharma
2.81
-4.98
-63.93%
FATE
Fate Therapeutics
0.91
-5.80
-86.44%
SRRK
Scholar Rock Holding
26.04
11.54
79.59%
IGMS
IGM Biosciences
1.12
-7.64
-87.21%
ATHA
Athira Pharma
0.25
-2.17
-89.67%
BDSX
Biodesix
0.58
-0.83
-58.87%

Lantern Pharma Earnings Call Summary

Earnings Call Date: Mar 27, 2025 | % Change Since: -19.62% | Next Earnings Date: May 6, 2025
Earnings Call Sentiment Neutral
Lantern Pharma has made notable advancements in AI-driven oncology drug development, achieving significant clinical trial milestones and regulatory designations. However, financial challenges persist with increased operational losses and future funding needs.
Highlights
AI and Machine Learning Integration
Lantern Pharma's leadership in using AI and machine learning to develop precision oncology therapies has been transformative, leading to significant advancements in their clinical pipeline and AI platform, RADR.
HARMONIC Trial Success
The HARMONIC trial for LP-300 reported an 86% clinical benefit rate and a 43% objective response rate in never-smoker non-small cell lung cancer patients, a significant achievement given the limited response to existing therapies.
Regulatory Achievements
Received two FDA Fast Track designations for LP-184 in glioblastoma and triple-negative breast cancer, along with three additional rare pediatric disease designations.
Strategic Geographic Expansion
Lantern Pharma expanded trials to Japan and Taiwan, accelerating patient enrollment due to higher incidence rates of non-small cell lung cancer among never-smokers.
Lowlights
Increased Operating Loss
Net loss for the full year 2024 was approximately $20.8 million, up from $16 million in 2023, reflecting increased R&D and administrative expenses.
Funding Needs
Despite a strong cash position of $24 million, Lantern Pharma anticipates needing substantial additional funding in the near future to continue operations and development.
Company Guidance
During the fourth quarter and fiscal year 2024 earnings call, Lantern Pharma provided a comprehensive update on its progress and strategic initiatives. The company highlighted significant advancements in its AI-driven precision oncology platform, RADR, which has enabled the rapid development of three AI-driven drugs into clinical trials. Notably, the Phase 2 HARMONIC trial for LP-300 demonstrated an 86% clinical benefit rate and a 43% objective response rate in non-small cell lung cancer patients who are never-smokers. The expansion into Japan and Taiwan is expected to accelerate enrollment for this $4 billion to $5 billion annual opportunity. Additionally, Lantern received FDA Fast Track designations for LP-184 in glioblastoma and triple-negative breast cancer, indicating potential for expedited development. Financially, the company reported R&D expenses of $4.3 million for Q4 2024, up from $3.6 million the previous year, and ended the year with $24 million in cash, cash equivalents, and marketable securities, providing a 12-month runway. The company plans to pursue additional funding opportunities in 2025 to support its ongoing operations and development efforts.

Lantern Pharma Corporate Events

Business Operations and StrategyFinancial Disclosures
Lantern Pharma Reports Q4 2024 Financial Results and AI Progress
Positive
Mar 27, 2025

On March 27, 2025, Lantern Pharma announced its financial results for the fourth quarter and full year ended December 31, 2024, alongside updates on its AI-driven drug candidates and operational progress. The company reported significant advancements in its clinical programs, including the HARMONIC™ trial for LP-300, which showed promising results in never-smoker NSCLC patients, and the continued progress of LP-184 and LP-284 in clinical trials. Lantern Pharma also highlighted its innovative AI capabilities, such as the RADR® platform surpassing 100 billion oncology-specific data points and the development of an AI-powered ADC module, which could significantly reduce development timelines and costs.

Executive/Board Changes
Lantern Pharma Extends CSO’s Employment Agreement
Neutral
Jan 10, 2025

Lantern Pharma Inc.’s Board of Directors has approved an amendment to the employment agreement for Kishor G. Bhatia, the Chief Scientific Officer. The amendment extends the agreement’s term to January 15, 2026, adjusts his working hours to 24 per week, and sets his annual base salary at $189,600, effective from the first pay period in January 2025.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.