Clinical TrialsThe unexpected safety signal and changes to KROS’ Phase 2 TROPOS study of cibotercept in pulmonary arterial hypertension significantly increases the clinical, regulatory, and commercial risk for this asset.
Safety ConcernsKeros announced that it was voluntarily halting the two higher-dosing arms of TROPOS, a phase 2 of cibotercept in PAH due to the emergence of pericardial effusion side effects.
Stock PerformanceThe announcement confounded the Street's and analyst's thesis toward the program which ultimately resulted in the stock closing -73.15%.