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Immatics N.V. (IMTX)
:IMTX

Immatics (IMTX) AI Stock Analysis

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Immatics

(NASDAQ:IMTX)

45Neutral
Immatics' strong revenue growth is overshadowed by its operational inefficiencies and negative cash flow, impacting its overall financial health. The stock's bearish technical indicators and high P/E ratio suggest caution. The lack of recent earnings call data or corporate events leaves the score driven primarily by fundamental and technical analyses.
Positive Factors
Clinical Data
Impressive data was reported for IMA203, with a 62% overall response rate and a 92% disease control rate in a heavily pre-treated metastatic melanoma patient group.
Financial Position
IMTX ended 4Q24 with $628.0M in cash and equivalents, providing a cash runway into 2H27.
Partnerships
Immatics N.V. continues to have ongoing partnerships with Editas Medicine and Moderna Therapeutics, which investors may view as an important source of external validation.
Pipeline Progress
IMTX confirmed that the Phase III SUPRAME study evaluating IMA203 in cutaneous melanoma has started to enroll patients and remains on track to complete enrollment by the end of 2026.
Negative Factors
Collaboration Termination
The termination by Bristol Myers Squibb of a collaboration with Immatics N.V. is seen as an incremental negative for the stock.
Equity Financing
IMTX shares dropped 16%, suspected to be related to the surprising decision to announce an equity financing.

Immatics (IMTX) vs. S&P 500 (SPY)

Immatics Business Overview & Revenue Model

Company DescriptionImmatics N.V., a clinical-stage biopharmaceutical company, focuses on the discovery and development of T cell receptor (TCR) based immunotherapies for the treatment of cancer in the United States. The company is developing targeted immunotherapies with a focus on treating solid tumors through two distinct treatment modalities, such as adoptive cell therapies (ACT) and antibody-like TCR Bispecifics. Its ACTengine product candidates are in Phase I clinical trials, which include IMA201 that targets melanoma-associated antigen 4 or 8 in patients with solid tumors; IMA202 that targets melanoma-associated antigen 1 in patients with various solid tumors, including squamous non-small cell lung carcinoma and hepatocellular carcinoma; and IMA203 that targets preferentially expressed antigen in melanoma in adult patients with relapsed and/or refractory solid tumors, as well as IMA204, which is in preclinical studies that targets tumor stroma cell. The company's TCR Bispecifics product candidates, which are in preclinical studies include IMA401, a cancer testis antigen for the treatment of solid tumors; and IMA402 for the treatment of solid tumors. It also develops IMA101 for the treatment of cancer; and IMA301, an allogenic cellular therapy product candidate. The company has a strategic collaboration agreement with GlaxoSmithKline Intellectual Property Development Limited to develop novel adoptive cell therapies targeting multiple cancer indications; MD Anderson Cancer Center to develop multiple T cell and TCR-based adoptive cellular therapies; Celgene Switzerland LLC to develop novel adoptive cell therapies targeting multiple cancers; and Genmab A/S to develop T cell engaging bispecific immunotherapies targeting multiple cancer indications. Immatics N.V. is headquartered in Tübingen, Germany.
How the Company Makes MoneyImmatics makes money primarily through a combination of research and development collaborations, licensing agreements, and milestone payments from its strategic partnerships with pharmaceutical companies. These partnerships often involve the co-development of TCR-based therapies where Immatics receives upfront payments, research funding, and potential future royalties based on sales if the therapies are successfully commercialized. Additionally, the company may earn revenue through government grants and funding for specific research initiatives. The success of its revenue model is largely dependent on the progress of its clinical trials and the ability to bring its therapies to market.

Immatics Financial Statement Overview

Summary
Immatics is experiencing financial difficulties typical of biotech firms. Despite strong revenue growth of 188.5%, profitability challenges persist with a net profit margin of 9.8% and negative EBIT margin of -24.8%. The balance sheet is strong with a low debt-to-equity ratio of 0.03 and an equity ratio of 82.6%, but low return on equity at 2.6% indicates limited profitability. Additionally, cash flow issues are significant with negative free cash flow and a reliance on external funding.
Income Statement
45
Neutral
Immatics has shown significant volatility in its income statement. The revenue growth from 2023 to 2024 was substantial at 188.5%, but profitability remains an issue with a net profit margin of 9.8% in 2024, despite the previous year's net loss. The gross profit margin improved drastically from negative to 100% in 2024, indicating effective cost management. However, the negative EBIT margin of -24.8% highlights ongoing operational challenges.
Balance Sheet
60
Neutral
The balance sheet of Immatics indicates strong equity and liquidity positions with a debt-to-equity ratio of 0.03, which is low for the industry. The equity ratio improved significantly to 82.6% in 2024, reflecting a solid foundation. However, the company's return on equity of 2.6% suggests limited profitability relative to its equity base.
Cash Flow
40
Negative
Immatics faces challenges in generating positive cash flow, as seen in the negative free cash flow of -$174.5 million in 2024, a deterioration from previous years. The operating cash flow to net income ratio is negative, indicating inefficiencies in cash generation from operations. The reliance on financing activities highlights a need for external funding.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
155.84M54.00M172.83M34.76M31.25M
Gross Profit
155.84M-64.67M66.05M-52.81M-35.83M
EBIT
-38.62M-101.72M29.95M-86.29M-69.72M
EBITDA
34.46M-88.93M50.04M-83.56M-64.44M
Net Income Common Stockholders
15.22M-96.99M37.51M-95.06M-229.35M
Balance SheetCash, Cash Equivalents and Short-Term Investments
604.45M425.89M362.20M145.12M231.98M
Total Assets
696.15M509.96M407.82M174.65M254.65M
Total Debt
16.20M15.40M14.56M9.85M6.19M
Net Debt
-220.54M-203.07M-133.96M-123.14M-201.34M
Total Liabilities
121.30M284.88M194.66M150.58M150.39M
Stockholders Equity
574.84M225.08M213.16M24.06M104.26M
Cash FlowFree Cash Flow
-174.51M-12.73M93.92M-87.44M-93.13M
Operating Cash Flow
-158.03M18.23M100.13M-81.78M-85.61M
Investing Cash Flow
-152.39M-31.39M-209.79M7.49M-15.95M
Financing Cash Flow
319.68M84.52M123.71M-2.61M207.88M

Immatics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.97
Price Trends
50DMA
4.69
Negative
100DMA
5.85
Negative
200DMA
8.49
Negative
Market Momentum
MACD
-0.13
Positive
RSI
33.37
Neutral
STOCH
11.30
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IMTX, the sentiment is Negative. The current price of 3.97 is below the 20-day moving average (MA) of 4.45, below the 50-day MA of 4.69, and below the 200-day MA of 8.49, indicating a bearish trend. The MACD of -0.13 indicates Positive momentum. The RSI at 33.37 is Neutral, neither overbought nor oversold. The STOCH value of 11.30 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for IMTX.

Immatics Risk Analysis

Immatics disclosed 84 risk factors in its most recent earnings report. Immatics reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Immatics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (48)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
48
Neutral
$6.36B1.28-45.04%2.64%19.24%1.69%
45
Neutral
$491.06M49.263.73%188.64%
45
Neutral
$482.11M-42.91%2.90%
43
Neutral
$475.14M-29.06%30.27%44.12%
39
Underperform
$473.01M-61.50%-44.25%
35
Underperform
$495.34M-238.46%71.17%23.89%
35
Underperform
$507.77M-99.54%-2.53%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IMTX
Immatics
3.97
-6.64
-62.58%
QURE
uniQure
8.57
3.79
79.29%
KURA
Kura Oncology
5.63
-13.85
-71.10%
SVRA
Savara
2.64
-2.43
-47.93%
COGT
Cogent Biosciences
4.02
-2.49
-38.25%
BCYC
Bicycle Therapeutics
6.53
-15.77
-70.72%
Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.