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Physiomics plc (GB:PYC)
:PYC

Physiomics (PYC) AI Stock Analysis

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Physiomics

(LSE:PYC)

44Neutral
Physiomics faces significant financial challenges, including declining revenue and negative profit margins. However, recent corporate events, such as fundraising and strategic collaborations, offer potential for growth and improved stability. Despite technical indicators showing a bearish trend, these positive developments could provide some support to the stock.

Physiomics (PYC) vs. S&P 500 (SPY)

Physiomics Business Overview & Revenue Model

Company DescriptionPhysiomics (PYC) is a healthcare and technology company specializing in the application of computational systems biology to improve drug development processes. It operates primarily in the biotechnology and pharmaceutical sectors, offering cutting-edge modeling and simulation services to optimize clinical trial designs and enhance drug development efficiency. Core services include Virtual Tumor technology and other predictive modeling tools that support decision-making in oncology drug development.
How the Company Makes MoneyPhysiomics makes money through service contracts with pharmaceutical and biotechnology companies, providing them with advanced modeling and simulation services to enhance their drug development processes. The company's key revenue streams are consultancy fees for their predictive modeling services, particularly in oncology, and licensing fees for their proprietary Virtual Tumor technology. Significant partnerships with leading pharmaceutical companies, which leverage Physiomics' expertise to accelerate and de-risk their drug development pipelines, contribute substantially to the company's earnings.

Physiomics Financial Statement Overview

Summary
Physiomics is facing significant financial challenges, with declining revenues, negative profit margins, and deteriorating cash flows. Although the company is debt-free, the reduction in equity and persistent losses indicate the need for strategic improvements to enhance financial health.
Income Statement
28
Negative
Physiomics has faced declining revenue over the years, with a negative revenue growth rate from 2023 to 2024. The company has consistently reported negative gross profit and net income, leading to unfavorable gross and net profit margins. The persistent negative EBIT and EBITDA margins further indicate operational challenges and inefficiencies.
Balance Sheet
45
Neutral
The company has managed to maintain a debt-free status, which is a positive aspect. However, the significant decline in stockholders' equity from 2023 to 2024 raises concerns about financial stability. The equity ratio has also decreased, reflecting a reduced ability to cover liabilities with equity.
Cash Flow
32
Negative
Physiomics has experienced deteriorating operating cash flow, with negative free cash flow reported consistently. The free cash flow growth rate is negative, and the operating cash flow to net income ratio is unfavorable, highlighting cash management issues.
Breakdown
Jun 2024Jun 2023Jun 2022Jun 2021Jun 2020
Income StatementTotal Revenue
543.25K597.35K830.27K702.31K799.05K
Gross Profit
-677.43K-581.62K-429.01K-365.79K-177.15K
EBIT
-670.82K-581.62K-429.01K-365.78K-177.15K
EBITDA
-659.80K-561.57K-347.84K-324.52K-124.71K
Net Income Common Stockholders
-609.35K-477.26K-253.14K-215.83K-64.42K
Balance SheetCash, Cash Equivalents and Short-Term Investments
191.07K416.59K687.67K1.04M1.05M
Total Assets
422.60K674.39K1.12M1.32M1.45M
Total Debt
0.000.000.000.000.00
Net Debt
-191.07K-416.59K-687.67K-1.04M-1.05M
Total Liabilities
140.08K142.67K140.61K157.57K131.52K
Stockholders Equity
282.53K531.72K974.81K1.17M1.31M
Cash FlowFree Cash Flow
-565.44K-271.50K-358.62K-48.65K-120.78K
Operating Cash Flow
-548.13K-264.86K-349.25K-32.50K-115.69K
Investing Cash Flow
-15.21K-6.22K-9.37K-16.15K-5.09K
Financing Cash Flow
337.83K0.002.85K44.24K763.28K

Physiomics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.42
Price Trends
50DMA
0.74
Negative
100DMA
0.72
Negative
200DMA
0.78
Negative
Market Momentum
MACD
-0.10
Negative
RSI
22.24
Positive
STOCH
11.11
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:PYC, the sentiment is Negative. The current price of 0.42 is below the 20-day moving average (MA) of 0.49, below the 50-day MA of 0.74, and below the 200-day MA of 0.78, indicating a bearish trend. The MACD of -0.10 indicates Negative momentum. The RSI at 22.24 is Positive, neither overbought nor oversold. The STOCH value of 11.11 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:PYC.

Physiomics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (49)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
49
Neutral
$6.90B-0.08-53.01%2.43%24.84%-3.06%
GBPYC
44
Neutral
£1.26M-116.39%-21.33%-2.50%
36
Underperform
£87.61M167.16%-100.00%-23.91%
GBSAR
32
Underperform
£20.61M-209.37%5.76%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:PYC
Physiomics
0.42
-0.88
-67.69%
GB:SCLP
Scancell Holdings
8.45
-2.05
-19.52%
GB:SAR
Sareum Holdings
16.50
-6.00
-26.67%

Physiomics Corporate Events

Private Placements and FinancingBusiness Operations and StrategyFinancial Disclosures
Physiomics Reports Interim Financial Results and Strategic Growth Initiatives
Neutral
Mar 6, 2025

Physiomics plc reported interim financial results for the six-month period ending December 31, 2024, showing a slight decrease in revenue and an increase in operating loss compared to the previous year. Despite these financial challenges, the company has established a strong pipeline with new contracts and expanded its service offerings, including the launch of a Biostatistics service line and the development of Personalized Medicine Dosing Software. The company completed a successful fundraising effort, enhancing its cash position, and is on track to meet market expectations for the year, driven by a robust second half and strategic growth initiatives.

Business Operations and StrategyFinancial Disclosures
Physiomics Announces Interim Results and Investor Presentation
Positive
Feb 28, 2025

Physiomics plc announced it will release its interim results on March 6, 2025, followed by a live investor presentation on March 10, 2025. This presentation, led by CEO Peter Sargent and Chairman Jim Millen, will be open to existing and potential shareholders, providing an opportunity to discuss the interim results and broader business aspects. This initiative reflects Physiomics’ commitment to transparency and engagement with its stakeholders, potentially enhancing its industry positioning and investor relations.

Other
Physiomics PLC Announces Change in Major Shareholder Holdings
Neutral
Feb 20, 2025

Physiomics PLC has announced a change in major holdings, indicating a shift in the company’s shareholder structure. Ryan Mancrief has sold his holdings at Barclays Investment Solutions Limited, now holding 14,234,711 shares in a nominee account at AJ Bell plc, which represents 4.6947% of the company’s issued share capital. This change reflects a decrease from a previous position of 8.5127% and may impact the company’s voting dynamics and influence among stakeholders.

Private Placements and FinancingBusiness Operations and Strategy
Physiomics Raises £500,000 to Fuel Growth and Expansion
Positive
Feb 17, 2025

Physiomics plc announced the successful completion of its WRAP Retail Offer, raising £70,000, which combined with a previous placing, totals £500,000 in gross proceeds. The funds will support the company’s growth, including recruitment for its consulting services, investment in business development, and the expansion of its personalized medicine tools, signifying an effort to bolster its industry position and service offerings.

Private Placements and FinancingBusiness Operations and Strategy
Physiomics plc Launches Retail Offer to Raise £70,000
Positive
Feb 13, 2025

Physiomics plc has announced a retail offer via the Winterflood Retail Access Platform to raise up to £70,000 through the issuance of new ordinary shares. This offer is part of a broader strategy to raise approximately £500,000 through a separate placing of new shares. The funds raised will support the company’s ongoing operations and strategic initiatives. The offer is targeted exclusively at existing retail shareholders in the UK, emphasizing the company’s commitment to its retail shareholder base. The offer is not contingent upon the completion of the separate placing, ensuring flexibility in capital acquisition. This initiative reflects Physiomics’ strategic approach to strengthening its financial position and enhancing shareholder value.

Private Placements and FinancingBusiness Operations and Strategy
Physiomics plc Secures £430,000 to Boost Growth and Innovation
Positive
Feb 13, 2025

Physiomics plc has successfully completed a £430,000 placing to fund growth opportunities, issuing 86,000,000 new ordinary shares at a 37.5% discount. The company is also launching a retail offer to raise an additional £70,000. The funds will support the recruitment of technical staff, business development, and strategic growth in their consulting services. The company has made progress with new contract awards and publications, and aims to further its personalized medicine tools in collaboration with DoseMe. Recent achievements include contract wins and high-profile collaborations, positioning the company for continued growth and new business opportunities in the biotech and pharma sectors.

Business Operations and StrategyFinancial Disclosures
Physiomics Reports Stable Performance and Reduced Losses for FY 2025
Neutral
Jan 30, 2025

Physiomics plc announced that it is performing in line with market expectations for the fiscal year ending June 2025, with anticipated income reflecting signed contracts and a slight reduction in expected losses due to improved operational efficiencies and maintained day rates with key customers. The company is in discussions for additional contracts but cannot guarantee they will be finalized within the current fiscal year. Interim results for the six months ending December 2024 are expected to be reported in early March 2025.

Business Operations and Strategy
Physiomics and Merck KGaA Publish Breakthrough Oncology Research
Positive
Jan 30, 2025

Physiomics plc announced the joint publication of a peer-reviewed article with Merck KGaA, showcasing a mathematical model to optimize combination oncology therapies. The publication highlights how Physiomics’ Virtual Tumour platform accelerates drug development by predicting effective experimental permutations, mitigating costs, and informing clinical trial designs. This collaboration underscores the company’s influential role in the development of innovative oncology treatments and its strong, longstanding partnership with Merck KGaA.

Other
Physiomics PLC Announces Major Shareholding Change
Neutral
Jan 28, 2025

Physiomics PLC has announced a significant change in its voting rights structure following the acquisition of shares by Ryan Mancrief. The notification reveals that Mr. Mancrief now holds an 8.5127% voting rights stake in the company, through shares held via AJ Bell plc and Barclays Investment Solutions Limited. This development could potentially influence company decisions and strategic directions, impacting stakeholders and the company’s positioning within the industry.

Physiomics and Astellas Collaborate on Immunotherapy Optimization Study
Jan 10, 2025

Physiomics plc announced a joint publication with Astellas Pharma Inc. in the journal ‘CPT: Pharmacometrics & Systems Pharmacology,’ detailing a study on optimizing treatment regimens for an oncolytic virus combined with Pembrolizumab. The study highlights the importance of dose and scheduling optimization in immunotherapy, a promising cancer treatment approach. The use of Physiomics’ Virtual Tumour platform demonstrates their capability to assist in developing innovative therapies by accelerating and de-risking the drug development process, reinforcing their position as a valuable partner for pharmaceutical companies in developing advanced cancer treatments.

Physiomics Secures Approval for PREDICT-ONC Clinical Trial
Jan 8, 2025

Physiomics plc announced that its Innovate UK funded project, PREDICT-ONC, has received both regulatory and ethical approval. This project aims to further develop their personalized dosing software which assists clinicians in optimizing chemotherapy dosing for individual patients. The software, initially designed for cancer chemotherapy dosing, has shown potential in predicting GCSF dosing to alleviate chemotherapy-induced neutropenia. Despite delays in the trial start, which were beyond the company’s control, recruitment is set to begin imminently, with minimal impact on the overall timeline anticipated.

Physiomics Strengthens Collaboration with Numab Therapeutics
Dec 12, 2024

Physiomics plc has announced a new contract with Numab Therapeutics AG, involving the use of Pharmacokinetic-Pharmacodynamic modelling to enhance a key asset in Numab’s pipeline. This collaboration underscores Physiomics’ expertise in modelling and simulation to expedite therapeutic development, reinforcing its position as a valuable partner in the drug development process.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.