Cue Biopharma stock analysis
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Cue Biopharma (CUE) Stock Price & Analysis
CUE Stock Chart & Stats
- Day’s Range
- $18.51 - $19.99
- 52-Week Range
- $4.95 - $45.50
- Previous Close
- $18.76
- Volume
- N/A
- Average Volume (3M)
- 163.66K
- Market Cap
- $136.28M
- Enterprise Value
- $191.53M
- Total Cash (Recent Filing)
- $17.39M
- Total Debt (Recent Filing)
- $8.81M
- Price to Earnings (P/E)
- ―
- Beta
- 3.26
- Next Earnings
- Nov 12, 2026 (Est.)
- EPS Estimate
- -2.24
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
CUE-221 Clinical Differentiation
Positive Phase 2 results strengthen the lead program’s development case by showing statistically significant, dose-responsive efficacy and benefit lasting after treatment ended. The favorable safety profile and planned registration-enabling study could improve the company’s opportunity to establish a differentiated allergy biologic.
Improving Revenue Trajectory
Meaningful multi-year revenue expansion indicates that Cue Biopharma is building greater commercial or collaboration-related activity despite remaining clinical-stage. Continued top-line scaling can improve operating leverage over time and provide a stronger base for funding research, development, and future product advancement.
Experienced Financial Leadership
Appointing an experienced life sciences CFO may strengthen capital-markets execution, financial controls, and preparation for the company’s next development stage. That expertise is relevant to managing financing needs and supporting disciplined execution as CUE-221 advances toward later-stage clinical development.
Bears Say
Heavy Cash Consumption
Sustained cash burn means Cue Biopharma is consuming substantial resources to maintain operations and advance its pipeline. Ongoing negative operating and free cash flow increases dependence on future financing or partnership proceeds, potentially limiting strategic flexibility and creating funding pressure over the next several quarters.
Deepening Operating Losses
Large and worsening operating and net losses show that current activity is not yet translating into sustainable profitability. Even with improving revenue and near break-even gross profit, insufficient cost absorption could prolong reliance on external capital and delay the point at which the business funds growth internally.
Equity Erosion And Financing Risk
Rapid equity erosion and shrinking assets weaken the balance sheet’s ability to support continued development. Although nominal debt remains modest, the reduced capital base and higher debt-to-equity relationship increase financing and dilution risk, making future capital allocation less flexible during clinical execution.
Cue Biopharma News
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Cue Biopharma Stock Smart Score
Company Description
Cue Biopharma
Cue Biopharma, Inc. is a clinical-stage biopharmaceutical enterprise focused on creating biological therapies. Its central objective is the precise manipulation of the human immune system to address a spectrum of severe conditions, such as various cancers, chronic infectious diseases, and autoimmune disorders. The company's leading investigational therapeutic is CUE-101, a specialized fusion protein biologic. This candidate is currently advancing through Phase 1b clinical trials, engineered to specifically identify and activate antigen-specific T cells involved in cancers originating from human papillomavirus. Beyond its flagship program, Cue Biopharma is also developing a range of other innovative platforms: CUE-102, another fusion protein biologic designed to stimulate specific T cells to combat cancer; CUE-103, an Immuno-STAT from the CUE-100 series, which is developed to target the KRAS G12V mutation relevant in diseases like colorectal, lung, and pancreatic cancers; CUE-200, which concentrates on cell surface receptors such as CD80 and/or 4-1BBL to counteract T cell exhaustion often seen in chronic infections; and the CUE-300 and CUE-400 frameworks, conceptual platforms aimed at treating diverse autoimmune conditions. Cue Biopharma maintains key strategic alliances, including collaborations with Merck Sharp & Dohme Corp. for the research and development of its unique biologics targeting autoimmune indications, with LG Chem Life Sciences for advancing Immuno-STATs in the field of oncology, and with the Albert Einstein College of Medicine. The company, founded in 2014, was initially known as Imagen Biopharma, Inc. before adopting its current name, Cue Biopharma, Inc., in October 2016. It is headquartered in Cambridge, Massachusetts.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Shao-Lee Lin
- Employees
- 29
- Website
- www.cuebiopharma.com
- Address
- 40 Guest Street, Boston, MA, 02135, US
Cue Biopharma (CUE) Earnings & Revenues
CUE Earnings Call
Earnings Call SentimentNeutral
The call presented several positive developments in clinical trials and strategic financial management, but also noted delays in trial launches and competitive market challenges.
View all CUE earnings summariesCUE Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 2 | 5 | 15 |
| Technical Analysis | 2 | 5 | 3 |
| Moving Averages | 0 | 0 | 12 |












