Encouraging Initial Data from CRDF-004 Trial
The trial showed a 64% ORR for patients on the 30 mg dose of onvansertib, compared to a 33% ORR in the control arm, indicating a strong efficacy signal.
Successful Capital Raise
Cardiff Oncology successfully completed a $40 million capital raise, enhancing financial stability and resources for future developments.
Advancement in Intellectual Property
A new patent was issued covering the use of onvansertib with bevacizumab for KRAS-mutated mCRC, extending intellectual property protection until at least 2043.
Strong Financial Position
Cash and short-term investments totaled $91.7 million, providing a financial runway into Q1 2027.
Positive Preclinical Results in Breast Cancer
Onvansertib showed promising results in preclinical studies, demonstrating synergistic activity with paclitaxel and ENHERTU in drug-resistant HR-positive breast cancer models.