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Compass Therapeutics, Inc. (CMPX)
NASDAQ:CMPX
US Market
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Compass Therapeutics (CMPX) AI Stock Analysis

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CMPX

Compass Therapeutics

(NASDAQ:CMPX)

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Neutral 45 (OpenAI - 5.2)
Rating:45Neutral
Price Target:
$2.50
▼(-58.33% Downside)
Action:Reiterated
Date:05/29/26
The score is primarily constrained by weak financial performance (pre-revenue, sizable losses, and ongoing free-cash-flow burn). Technicals also remain pressured by a broader downtrend and negative MACD despite a short-term bounce. Valuation is difficult to support with a negative P/E and no dividend yield.
Positive Factors
Positive Phase 2/3 clinical results
Robust randomized Phase 2/3 results in second-line biliary tract cancer materially de-risk a lead program. Statistically significant PFS and improved ORR in a disease lacking approved second-line options strengthen regulatory and commercial prospects, boost partnering appeal, and support a durable pathway to potential product revenue and lifecycle planning.
Negative Factors
Pre-revenue, large persistent losses
As a pre-revenue clinical-stage biotech, Compass lacks product-derived cash flow and records large recurring net losses. This structural profitability gap means the company must rely on financing or partnerships to fund operations; absent durable revenue, operational sustainability depends on advancing candidates to approval or securing material non-dilutive deals.
Read all positive and negative factors
Positive Factors
Negative Factors
Positive Phase 2/3 clinical results
Robust randomized Phase 2/3 results in second-line biliary tract cancer materially de-risk a lead program. Statistically significant PFS and improved ORR in a disease lacking approved second-line options strengthen regulatory and commercial prospects, boost partnering appeal, and support a durable pathway to potential product revenue and lifecycle planning.
Read all positive factors

Compass Therapeutics (CMPX) vs. SPDR S&P 500 ETF (SPY)

Compass Therapeutics Business Overview & Revenue Model

Company Description
Compass Therapeutics, Inc., a clinical-stage oncology-focused biopharmaceutical company, engages in developing antibody-based therapeutics to treat various human diseases. The company's product candidates in the clinical stage of development inclu...
How the Company Makes Money
Compass Therapeutics is a clinical-stage biotech and, as such, it generally does not generate recurring revenue from product sales unless and until a drug candidate receives regulatory approval; the primary funding source is typically external fin...

Compass Therapeutics Financial Statement Overview

Summary
Financials reflect an early-stage biotech profile: minimal revenue (TTM $0) with large, persistent losses (TTM net income -$68.2M) and significant cash burn (TTM FCF -$53.3M). The balance sheet is a partial offset with low leverage (debt-to-equity ~0.05) and meaningful equity, but the trend of worsening operating cash outflow increases financing/dilution risk.
Income Statement
12
Very Negative
Balance Sheet
62
Positive
Cash Flow
23
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.00850.00K0.000.000.00
Gross Profit-738.00K-1.47M850.00K0.000.000.00
EBITDA-72.49M-71.37M-54.87M-48.47M-39.75M-80.19M
Net Income-68.17M-66.49M-49.38M-42.49M-39.23M-82.18M
Balance Sheet
Total Assets205.17M219.59M140.40M156.88M199.65M153.76M
Cash, Cash Equivalents and Short-Term Investments194.69M208.91M126.72M152.46M186.61M144.51M
Total Debt9.79M9.83M6.63M1.73M2.94M4.04M
Total Liabilities18.70M22.80M15.17M8.34M18.01M13.68M
Stockholders Equity186.47M196.79M125.23M148.54M181.64M140.08M
Cash Flow
Free Cash Flow-53.29M-49.17M-44.90M-40.65M-34.34M-21.23M
Operating Cash Flow-53.20M-49.14M-44.85M-40.62M-34.13M-19.67M
Investing Cash Flow-66.47M-93.31M46.77M26.96M-151.20M-1.77M
Financing Cash Flow133.79M129.61M17.34M2.94M75.76M118.61M

Compass Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price6.00
Price Trends
50DMA
3.68
Negative
100DMA
4.79
Negative
200DMA
4.50
Negative
Market Momentum
MACD
-0.36
Negative
RSI
40.21
Neutral
STOCH
82.81
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CMPX, the sentiment is Negative. The current price of 6 is above the 20-day moving average (MA) of 2.00, above the 50-day MA of 3.68, and above the 200-day MA of 4.50, indicating a neutral trend. The MACD of -0.36 indicates Negative momentum. The RSI at 40.21 is Neutral, neither overbought nor oversold. The STOCH value of 82.81 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CMPX.

Compass Therapeutics Risk Analysis

Compass Therapeutics disclosed 76 risk factors in its most recent earnings report. Compass Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Compass Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$1.43B-9.83-1057.44%-13.14%
53
Neutral
$783.73M-10.34-36.61%-75.91%-173.33%
53
Neutral
$435.71M-36.68-12.84%40.38%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$326.93M-1.44-35.74%146.03%-0.87%
45
Neutral
$428.61M-6.07-39.75%-100.00%-2.72%
43
Neutral
$54.19M-0.26174.85%-55.42%-248.85%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CMPX
Compass Therapeutics
2.22
0.08
3.74%
KALV
KalVista Pharmaceuticals
26.94
13.59
101.80%
CTMX
CytomX Therapeutics
3.45
0.80
30.19%
GOSS
Gossamer Bio
0.20
-1.02
-83.61%
BCYC
Bicycle Therapeutics
4.53
-3.77
-45.42%
MNPR
Monopar Therapeutics Inc
61.26
29.15
90.78%

Compass Therapeutics Corporate Events

Business Operations and StrategyProduct-Related Announcements
Compass Therapeutics Reports Positive Phase 2/3 BTC Results
Positive
Apr 27, 2026
On April 27, 2026, Compass Therapeutics reported full secondary endpoint data from its COMPANION-002 randomized Phase 2/3 trial of tovecimig plus paclitaxel versus paclitaxel alone in 168 patients with second-line biliary tract cancer. The combina...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 29, 2026