Clinical RisksRisks include negative clinical data readouts, inability to advance CT1812 into pivotal trials in a timely manner, and failure to generate favorable top-line data from pivotal trials.
Financial PerformanceThe company recorded a net loss of $0.25 per share, substantively wider than forecasted net loss of only $0.16 per share, mainly driven by higher-than-anticipated R&D spending.
Treatment Efficacy VariabilityPatients with p-tau217 above median levels demonstrated similar ADAS-Cog-11 changes from baseline compared to placebo, with CT1812 treatment being slightly worse than placebo.